2-(4-Hydroxy-3-nitrophenyl)butanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-(4-Hydroxy-3-nitrophenyl)butanoate
• 英文别名: 2-(4-hydroxy-3-nitrophenyl)butanoate
• 化学式: C10H10NO5-
• 分子量: 224.19
• InChiKey: PWSAEPCSFKMBBD-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  106
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• ASSAYS FOR DETECTING GLUCOSIDASE ACTIVITY
  申请人：Megazme International Ireland

  公开号：US20150140573A1

  公开（公告）日：2015-05-21

  The present invention relates to a method of detecting α-(1→6)-glucosidase activity in a sample. The method is for example useful for determining the limit dextrinase activity in a sample. The method involves use of an oligosaccharide substrate of the formula X-(glucoside)n-*(glucoside)m-Z—Y, where X is a blocking group, -* is a α-(1→6)-glucosidic linkage and Y is a detectable label. Upon cleavage of the α-(1→6)-glucosidic linkage, the detectable label is released and thus the α-(1→6)-glucosidase activity can be determined. The invention also relates to the oligosaccharide substrate per se.

  本发明涉及一种检测样品中α-(1→6)-葡萄糖苷酶活性的方法。该方法例如可用于确定样品中极限糊精酶活性。该方法涉及使用式子为X-(葡萄糖苷)n-*(葡萄糖苷)m-Z-Y的寡糖基质，其中X是阻断基，-*是α-(1→6)-葡萄糖苷键，Y是可检测标记。在α-(1→6)-葡萄糖苷键的裂解后，可检测标记被释放，从而可以确定α-(1→6)-葡萄糖苷酶活性。本发明还涉及该寡糖基质本身。
• [EN] ASSAYS FOR DETECTING GLUCOSIDASE ACTIVITY<br/>[FR] ESSAIS POUR LA DÉTECTION D'ACTIVITÉ DE GLUCOSIDASE
  申请人：CARLSBERG AS CARLSBERG FORSKNINGSCT

  公开号：WO2013185771A1

  公开（公告）日：2013-12-19

  The present invention relates to a method of detecting α-(1→6)-glucosidase activity in a sample. The method is for example useful for determining the limit dextrinase activity in a sample. The method involves use of an oligosaccharide substrate of the formula X- (glucoside) n -*(glucoside) m -Z-Y, where X is a blocking group, -* is a α-(1→6)-glucosidic linkage and Y is a detectable label. Upon cleavage of the α-(1→6)-glucosidic linkage, the detectable labelis released and thus the α-(1→6)-glucosidase activity can be determined. The invention also relates to the oligosaccharide substrate per se.