Ethyl 2-pyrazolo[1,5-a]pyrimidin-6-ylacetate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡唑并嘧啶类
• 英文名称: Ethyl 2-pyrazolo[1,5-a]pyrimidin-6-ylacetate
• 英文别名: ethyl 2-pyrazolo[1,5-a]pyrimidin-6-ylacetate
• 化学式: C₁₀H₁₁N₃O₂
• 分子量: 205.21
• InChiKey: BAIRKORQDKWZRF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  56.5
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• 7-OXO-THIAZOLOPYRIDINE CARBONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE
  申请人：Savira Pharmaceuticals GmbH

  公开号：EP2864338A2

  公开（公告）日：2015-04-29
• [EN] 7-OXO-THIAZOLOPYRIDINE CARBONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE<br/>[FR] DÉRIVÉS D'ACIDE 7-OXOTHIAZOLOPYRIDINE CARBONIQUE ET LEUR UTILISATION DANS LE TRAITEMENT, L'AMÉLIORATION OU LA PRÉVENTION D'UNE MALADIE VIRALE
  申请人：SAVIRA PHARMACEUTICALS GMBH

  公开号：WO2013174930A2

  公开（公告）日：2013-11-28

  The present invention relates to a compound having the general formula (A), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, codrug, cocrystal, prodrug, tautomer, racemate, enantiomer, or diasiereomer or mixture thereof, which are useful in treating, ameloriating or preventing a viral disease. Furthermore, specific combination therapies are disclosed.