(8S,9S,10R,13R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-3-nitroso-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (8S,9S,10R,13R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-3-nitroso-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene
• 化学式: C₂₇H₄₅NO
• 分子量: 399.7
• InChiKey: ZJTGHVIALBGXAQ-UHZSGAEPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.5
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  29.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] BRANCHED POLYAMINES FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALS<br/>[FR] POLYAMINES RAMIFIÉES POUR L'ADMINISTRATION DE MATIÈRES BIOLOGIQUEMENT
  申请人：IBM

  公开号：WO2014042920A1

  公开（公告）日：2014-03-20

  A branched polyamine comprises about 45 to about 70 backbone tertiary amine groups, about 90 to about 140 backbone secondary amine groups, a positive number n' greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): — CH2-CH2-N— Is. ^O-L'-O H (2), wherein (n'+q) is a number equal to about 45 to about 70, the starred bond of formula (2) is linked to a backbone nitrogen of the branched polyamine, L' is a divalent radical comprising 3 to 30 carbons, and q/(n' + q) x 100% equals about 9% to about 47%.