N'-methyl-N-(2-methylbutan-2-yl)methanimidamide

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N'-methyl-N-(2-methylbutan-2-yl)methanimidamide
• 化学式: C₇H₁₆N₂
• 分子量: 128.22
• InChiKey: YIAFOBVQROUBCW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  24.4
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• INHIBITORS OF KRAS G12C AND METHODS OF USING THE SAME
  申请人：Amgen Inc.

  公开号：US20200207766A1

  公开（公告）日：2020-07-02

  Provided herein are methods of using KRAS G12C inhibitors. These methods of using the inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
• [EN] METHOD OF TREATMENT OR PROPHYLAXIS OF INFECTIONS OF THE EYE<br/>[FR] PROCÉDÉ DE TRAITEMENT OU DE PRÉVENTION D'INFECTIONS OCULAIRES
  申请人：STARPHARMA PTY LTD

  公开号：WO2014043576A1

  公开（公告）日：2014-03-20

  A microbial infection in an eye of a subject is treated or prevented by topically administering to the eye an effective amount of a macromolecule or a pharmaceutically acceptable salt thereof that includes a dendrimer of 1 to 8 generations with one or more sulfonic acid- or sulfonate-containing moieties attached to one or more surface groups of the outermost generation of the dendrimer. Compositions containing the macromolecule or salt are useful in these methods.