The present invention provides methods and materials related to the detection of colorectal neoplasm-specific markers in or associated with a subject's stool sample. In particular, the present invention provides methods and materials for identifying mammals having a colorectal neoplasm by detecting the presence of exfoliated epithelial markers (e.g., human DNA, tumor assoicated gene alterations, tumor associated proteins) and blood markers (e.g., homoglobin, serum proteins) in a stool sample obtained from the mammal.
本发明提供了与检测受试者粪便样本中或与之相关的结直肠肿瘤特异性标记物有关的方法和材料。特别是,本发明提供了通过检测哺乳动物粪便样本中是否存在脱落上皮标记物(如人类 DNA、肿瘤相关
基因改变、肿瘤相关蛋白)和血液标记物(如同型血红蛋白、血清蛋白)来鉴定哺乳动物是否患有结直肠肿瘤的方法和材料。