tert-butyl N-[2-[4-(2-fluoroethylamino)phenyl]ethyl]carbamate

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: tert-butyl N-[2-[4-(2-fluoroethylamino)phenyl]ethyl]carbamate
• 化学式: C₁₅H₂₃FN₂O₂
• 分子量: 282.35
• InChiKey: GSVVORKTHBFTKG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  20
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  50.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Compositions targeting bradykinin receptor B1 for medical imaging of cancer and other disorders
  申请人：BRITISH COLUMBIA CANCER AGENCY BRANCH

  公开号：US10039846B2

  公开（公告）日：2018-08-07

  Bradykinin B1 receptor (B1R) targeting peptides and compounds are radiolabelled with radioisotopes that are suitable for imaging and/or radiotherapy. The radiolabelled peptides and compounds have utility in imaging tissues expressing or overexpressing B1R and/or treating diseases or conditions in which B1R is expressed or overexpressed, including cancer.

  缓激肽 B1 受体（B1R）靶向肽和化合物被放射性同位素标记，适用于成像和/或放射治疗。放射性标记的肽和化合物可用于表达或过度表达 B1R 的组织的成像和/或治疗 B1R 表达或过度表达的疾病或病症，包括癌症。
• COMPOSITIONS TARGETING BRADYKININ RECEPTOR B1 FOR MEDICAL IMAGING OF CANCER AND OTHER DISORDERS
  申请人：Provincial Health Services Authority

  公开号：EP2895204B1

  公开（公告）日：2020-10-21
• [EN] COMPOSITIONS TARGETING BRADYKININ RECEPTOR B1 FOR MEDICAL IMAGING OF CANCER AND OTHER DISORDERS<br/>[FR] COMPOSITIONS CIBLANT LE RÉCEPTEUR B1 DE LA BRADYKININE POUR L'IMAGERIE MÉDICALE DU CANCER ET D'AUTRES TROUBLES
  申请人：BRITISH COLUMBIA CANCER AGENCY

  公开号：WO2014040192A1

  公开（公告）日：2014-03-20

  Bradykinin B1 receptor (B1R) targeting peptides and compounds are radiolabelled with radioisotopes that are suitable for imaging and/or radiotherapy. Said radiolabelled peptides and compounds have utility in imaging tissues expressing or overexpressing B1R and/or treating diseases or conditions in which B1R is expressed or overexpressed, including cancer.