(2E)-N-prop-1-en-2-ylpenta-2,4-dien-2-amine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (2E)-N-prop-1-en-2-ylpenta-2,4-dien-2-amine
• 化学式: C₈H₁₃N
• 分子量: 123.2
• InChiKey: VZDDJMWXURPSMZ-SOFGYWHQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS<br/>[FR] BIOCATALYSEURS DE NITRATION AUTO-SUFFISANTS HAUTEMENT ACTIFS
  申请人：UNIV FLORIDA

  公开号：WO2018081456A1

  公开（公告）日：2018-05-03

  The disclosure relates to the field of fusion proteins. In some aspects, the disclosure relates to artificial fusion proteins comprising cytochrome P450 enzymes linked to reductase enzymes and uses thereof. In some aspects, the disclosure relates to compounds produced by artificial cytochrome P450 enzymes.

  该披露涉及融合蛋白的领域。在某些方面，该披露涉及人工融合蛋白，其中包括与还原酶酶相连的细胞色素P450酶，并其用途。在某些方面，该披露涉及由人工细胞色素P450酶产生的化合物。
• NOVEL PHOSPHODIESTERASE INHIBITORS AND USES THEREOF
  申请人：The Trustees of Columbia University in the City of New York

  公开号：EP3022205B1

  公开（公告）日：2020-02-05
• [EN] NOVEL SIGMA RECEPTOR LIGANDS AND METHODS OF MODULATING CELLULAR PROTEIN HOMEOSTASIS USING SAME<br/>[FR] NOUVEAUX LIGANDS DU RÉCEPTEUR SIGMA ET PROCÉDÉS DE MODULATION DE L'HOMÉOSTASE DE PROTÉINE CELLULAIRE À L'AIDE DE CEUX-CI
  申请人：PHILADELPHIA HEALTH & EDUCATIO

  公开号：WO2014015157A2

  公开（公告）日：2014-01-23

  The present invention includes compounds useful in preventing, treating or ameliorating Sigma-related disorders or diseases. The compounds of the invention may modulate cellular protein homeostasis, which includes: translation initiation, folding, processing, transport, and degradation (including ubiquitin selective autophagy) of proteins. The present invention also includes methods of preventing, treating or ameliorating a Sigma-related disorder or disease in a subject in need thereof, the method comprising administering to the subject an effective amount of a Sigma-modulating compound. The present invention also includes methods of preventing, treating or ameliorating a Sigma-related disorder or disease in a subject in need thereof, the method comprising administering to the subject an effective amount of a Sigma-modulating compound, further comprising administering an effective amount of a compound that inhibits the ubiquitin proteasome system (UPS) and/or autophagic survival pathways.
• [EN] ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S<br/>[FR] CYTOCHROMES P450 AUTOSUFFISANTS ARTIFICIELS
  申请人：UNIV FLORIDA

  公开号：WO2016134145A9

  公开（公告）日：2017-02-16

  [EN] The disclosure relates to the field of fusion proteins. In some aspects, the invention relates to artificial fusion proteins comprising cytochrome P450 enzymes linked to reductase enzymes and uses thereof. In some aspects, the disclosure relates to compounds produced by artificial cytochrome P450 enzymes.
  [FR] La présente invention se rapporte au domaine des protéines hybrides. Dans certains aspects, l'invention concerne des protéines hybrides artificielles comprenant des enzymes du cytochrome P450 liées à des enzymes réductase et leurs utilisations. Dans certains aspects, l'invention concerne des composés produits par des enzymes du cytochrome P450 artificielles.
• [EN] WHOLE CELL PROCESSES TO PRODUCE NITROAROMATICS<br/>[FR] PROCÉDÉS UTILISANT DES CELLULES ENTIÈRES POUR PRODUIRE DES NITROAROMATIQUES
  申请人：UNIV FLORIDA

  公开号：WO2019183358A2

  公开（公告）日：2019-09-26

  The disclosure relates, in some aspects, to compositions and methods useful for production of nitrated aromatic molecules. The disclosure is based, in part, on whole cell systems expressing artificial fusion proteins comprising cytochrome P450 enzymes linked to reductase enzymes. In some aspects, the disclosure relates to methods of producing nitrated aromatic molecules in whole cell systems having artificial fusion proteins comprising cytochrome P450 enzymes linked to reductase enzymes.