5-[diethoxy(oxido)phosphaniumyl]-7-phenyl-5H-[1,3]dioxolo[4,5-g]isochromene | 1042369-62-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 5-[diethoxy(oxido)phosphaniumyl]-7-phenyl-5H-[1,3]dioxolo[4,5-g]isochromene
• CAS: 1042369-62-9
• 化学式: C₂₀H₂₁O₆P
• 分子量: 388.357
• InChiKey: VYXBQCOWMPVDFG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  69.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  亚磷酸二乙酯 、 6-(phenylethynyl)benzo[d][1,3]dioxole-5-carbaldehyde 在 silver trifluoromethanesulfonate 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 7.0h， 以87%的产率得到5-[diethoxy(oxido)phosphaniumyl]-7-phenyl-5H-[1,3]dioxolo[4,5-g]isochromene
  参考文献：
  名称：

  Synthesis of 1H-isochromen-1-ylphosphonates via AgOTf-catalyzed reaction of 2-alkynylbenzaldehyde with diethyl phosphite

  摘要：

  Tandem cyclization-addition reaction of 2-alkynylbenzaldehyde with diethyl phosphite catalyzed by AgOTf at room temperature was developed, which afforded the desired 1H-isochromen-1-ylphosphonates in moderate to good yields. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.05.009

文献信息

• Synthesis of 1H-isochromen-1-ylphosphonates via AgOTf-catalyzed reaction of 2-alkynylbenzaldehyde with diethyl phosphite
  作者：Xingxin Yu、Qiuping Ding、Weizi Wang、Jie Wu

  DOI：10.1016/j.tetlet.2008.05.009

  日期：2008.7

  Tandem cyclization-addition reaction of 2-alkynylbenzaldehyde with diethyl phosphite catalyzed by AgOTf at room temperature was developed, which afforded the desired 1H-isochromen-1-ylphosphonates in moderate to good yields. (C) 2008 Elsevier Ltd. All rights reserved.