(5,7-Difluoro-1,2,3,4-tetrahydronaphthalen-1-yl) ethanesulfonate

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: (5,7-Difluoro-1,2,3,4-tetrahydronaphthalen-1-yl) ethanesulfonate
• 英文别名: (5,7-difluoro-1,2,3,4-tetrahydronaphthalen-1-yl) ethanesulfonate
• 化学式: C₁₂H₁₄F₂O₃S
• 分子量: 276.3
• InChiKey: YDNKJKZPEJTDBF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  51.8
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Methods for Treating Dependence
  申请人：Biotie Therapies, Inc.

  公开号：US20140099336A1

  公开（公告）日：2014-04-10

  Provided are methods of treating patients suffering from or susceptible to at least one symptom of abuse of, dependence on, or withdrawal from at least one substance with Compound A. Also provided are methods of treating at least one phase of substance dependence on at least one substance in patients and certain methods of treating at least one phase of cocaine dependence in patients.

  提供了使用化合物A治疗患有或易感受到至少一种物质滥用、依赖或戒断症状的患者的方法。还提供了治疗患者至少一种物质依赖的至少一阶段的方法，以及治疗患者可卡因依赖的至少一阶段的特定方法。
• Methods for treating dependence
  申请人：Biotie Therapies, Inc.

  公开号：US10561638B2

  公开（公告）日：2020-02-18

  Provided are methods of treating patients suffering from or susceptible to at least one symptom of abuse of, dependence on, or withdrawal from at least one substance with Compound A. Also provided are methods of treating at least one phase of substance dependence on at least one substance in patients and certain methods of treating at least one phase of cocaine dependence in patients.

  还提供了治疗患者对至少一种物质的至少一个阶段的物质依赖的方法，以及治疗患者对可卡因的至少一个阶段的依赖的某些方法。