1-Methoxy-2-methyl-4-(4-octylphenyl)butan-2-amine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-Methoxy-2-methyl-4-(4-octylphenyl)butan-2-amine
• 英文别名: 1-methoxy-2-methyl-4-(4-octylphenyl)butan-2-amine
• 化学式: C₂₀H₃₅NO
• 分子量: 305.5
• InChiKey: PAPNYIXMQJLABM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  22
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• USE OF SPHINGOID LONG CHAIN BASES AND THEIR ANALOGS IN TREATING AND PREVENTING BACTERIAL INFECTIONS
  申请人：Yeda Research and Development Co., Ltd.

  公开号：EP2906570A1

  公开（公告）日：2015-08-19
• [EN] USE OF SPHINGOID LONG CHAIN BASES AND THEIR ANALOGS IN TREATING AND PREVENTING BACTERIAL INFECTIONS<br/>[FR] UTILISATION DE BASES À CHAÎNES LONGUES SPHINGOÏDES ET DE LEURS ANALOGUES DANS LE TRAITEMENT ET LA PRÉVENTION D'INFECTIONS BACTÉRIENNES
  申请人：YEDA RES & DEV

  公开号：WO2014061016A1

  公开（公告）日：2014-04-24

  Methods of preventing or treating bacterial infections, including but not limited to Pseudomonas aeruginosa infections, by administering sphingoid long chain bases (LCB) are provided. The invention further relates to the use of sphingoid long chain bases, or pharmaceutical composition comprising same, for the treatment of lung diseases or disorders such as cystic fibrosis and chronic obstructive pulmonary disease.