[1-[[3-(Adamantane-1-carbonyl)-2-(4-fluorophenyl)-1-benzothiophen-6-yl]oxymethyl]cyclopropyl]methyl nitrate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: [1-[[3-(Adamantane-1-carbonyl)-2-(4-fluorophenyl)-1-benzothiophen-6-yl]oxymethyl]cyclopropyl]methyl nitrate
• 英文别名: [1-[[3-(adamantane-1-carbonyl)-2-(4-fluorophenyl)-1-benzothiophen-6-yl]oxymethyl]cyclopropyl]methyl nitrate
• 化学式: C30H30FNO5S
• 分子量: 535.6
• InChiKey: JIHHOJZTDAPTNG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  38
• 可旋转键数：
  8
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  110
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS
  申请人：THATCHER Gregory R.

  公开号：US20150284357A1

  公开（公告）日：2015-10-08

  Disclosed is a compound of formula (I). or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions including the compound of formula (I) and methods of using the compound of formula (I).

  本发明揭示了一种式（I）的化合物或其药学上可接受的盐。还揭示了包括该式（I）化合物的药物组合物以及使用该式（I）化合物的方法。
• Compositions and methods for treating estrogen-related medical disorders
  申请人：THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

  公开号：US10160752B2

  公开（公告）日：2018-12-25

  Disclosed is a compound of formula (I). or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions including the compound of formula (I) and methods of using the compound of formula (I).

  公开了一种式（I）化合物或其药学上可接受的盐。还公开了包括式（I）化合物的药物组合物和式（I）化合物的使用方法。
• [EN] COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS<br/>[FR] COMPOSITIONS ET PROCÉDÉS PERMETTANT DE TRAITER DES AFFECTIONS MÉDICALES ASSOCIÉES AUX ŒSTROGÈNES
  申请人：UNIV ILLINOIS

  公开号：WO2014066695A1

  公开（公告）日：2014-05-01

  Disclosed is a compound of formula (I). or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions including the compound of formula (I) and methods of using the compound of formula (I).