3,5-Dimethyloctadecyl(octadecyl)azanium;bromide

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 3,5-Dimethyloctadecyl(octadecyl)azanium;bromide
• 英文别名: 3,5-dimethyloctadecyl(octadecyl)azanium;bromide
• 化学式: C38H80BrN
• 分子量: 631.0
• InChiKey: JKHWRXIJVXWTSW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.57
• 重原子数：
  40
• 可旋转键数：
  34
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  16.6
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• M. TUBERCULOSIS VACCINES
  申请人：Statens Serum Institut

  公开号：EP2912056A2

  公开（公告）日：2015-09-02
• NEW M.TUBERCULOSIS VACCINES
  申请人：Statens Serum Institut

  公开号：EP3134116B1

  公开（公告）日：2019-04-03
• [EN] M. TUBERCULOSIS VACCINES<br/>[FR] VACCINS DE M. TUBERCULOSIS
  申请人：STATENS SERUMINSTITUT

  公开号：WO2014063704A2

  公开（公告）日：2014-05-01

  The present invention is directed to fusion proteins, antigen cocktails and immunological compositions such as vaccines against infections caused by virulent mycobacteria, e.g. by Mycobacterium tuberculosis, Mycobacterium africanum, Mycobacterium bovis, Mycobacterium microti, Mycobacterium canettii, Mycobacterium pinnipedii or Mycobacterium mungi. The fusion proteins or antigen cocktails are based on ESX secreted or associated proteins e.g. proteins secreted by the ESAT-6 secretion system 1 (ESX-1 ) which are among the most immunodominant M. tuberculosis (MTB) antigens.
• [EN] NEW M.TUBERCULOSIS VACCINES<br/>[FR] NOUVEAUX VACCINS CONTRE M. TUBERCULOSIS
  申请人：STATENS SERUMINSTITUT

  公开号：WO2015161853A1

  公开（公告）日：2015-10-29

  The present invention is directed to a fusion protein, antigen cocktails and immunological compositions such as vaccines against infections caused by virulent mycobacteria, e.g. by Mycobacterium tuberculosis, Mycobacterium africanum, Mycobacterium bovis, Mycobacterium microti, Mycobacterium canettii, Mycobacterium pinnipedii or Mycobacterium mungi. The fusion protein, antigen cocktails and immunological compositions are based on proteins secreted by the ESAT-6 secretion system 1 (ESX-1) and are among the most immunodominant M. tuberculosis (MTB) antigens.