1-[2-(4-Fluorophenyl)-6-[(1-methylcyclopropyl)methoxy]-1-benzothiophen-3-yl]-2-methylpropan-1-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: 1-[2-(4-Fluorophenyl)-6-[(1-methylcyclopropyl)methoxy]-1-benzothiophen-3-yl]-2-methylpropan-1-one
• 英文别名: 1-[2-(4-fluorophenyl)-6-[(1-methylcyclopropyl)methoxy]-1-benzothiophen-3-yl]-2-methylpropan-1-one
• 化学式: C₂₃H₂₃FO₂S
• 分子量: 382.5
• InChiKey: PODGVMKQMHDQFI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  54.5
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS
  申请人：The Board of Trustees of the University of Illinois

  公开号：EP3192795A1

  公开（公告）日：2017-07-19

  Disclosed is a compound of formula (I) or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions including the compound of formula (I) and methods of using the compound of formula (I).

  公开了一种式 (I) 的化合物 或其药学上可接受的盐。还公开了包括式（I）化合物的药物组合物和式（I）化合物的使用方法。
• [EN] COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS<br/>[FR] COMPOSITIONS ET PROCÉDÉS PERMETTANT DE TRAITER DES AFFECTIONS MÉDICALES ASSOCIÉES AUX ŒSTROGÈNES
  申请人：UNIV ILLINOIS

  公开号：WO2014066695A1

  公开（公告）日：2014-05-01

  Disclosed is a compound of formula (I). or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions including the compound of formula (I) and methods of using the compound of formula (I).