[3-(4-Methyl-3-oxoquinoxalin-2-yl)-3-oxopropyl]-(1-phenylethenoxymethoxy)phosphinic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: [3-(4-Methyl-3-oxoquinoxalin-2-yl)-3-oxopropyl]-(1-phenylethenoxymethoxy)phosphinic acid
• 英文别名: [3-(4-methyl-3-oxoquinoxalin-2-yl)-3-oxopropyl]-(1-phenylethenoxymethoxy)phosphinic acid
• 化学式: C₂₁H₂₁N₂O₆P
• 分子量: 428.4
• InChiKey: NUYBWPPKPIFJEL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  30
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  106
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF
  申请人：Tadesse Dawit

  公开号：US20140128346A1

  公开（公告）日：2014-05-08

  The disclosure relates to Phosphorus-Substituted Quinoxaline-Type Piperidine Compounds of Formula (I): and pharmaceutically acceptable derivatives thereof wherein the dashed line, A, B, Q, R 1 , R 2 , R 3 , R 4 , Y 1 , Z, and a are as defined herein, compositions comprising an effective amount of a Phosphorus-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Phosphorus-Substituted Quinoxaline-Type Piperidine Compound.
• US9598447B2
  申请人：——

  公开号：US9598447B2

  公开（公告）日：2017-03-21