3-(4-diethoxyphosphoryl-3,6-dihydro-2H-pyridin-1-yl)-1-methylquinoxalin-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 3-(4-diethoxyphosphoryl-3,6-dihydro-2H-pyridin-1-yl)-1-methylquinoxalin-2-one
• 化学式: C₁₈H₂₄N₃O₄P
• 分子量: 377.4
• InChiKey: LRXRKTGRXCFAOG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  71.4
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF
  申请人：Tadesse Dawit

  公开号：US20140128346A1

  公开（公告）日：2014-05-08

  The disclosure relates to Phosphorus-Substituted Quinoxaline-Type Piperidine Compounds of Formula (I): and pharmaceutically acceptable derivatives thereof wherein the dashed line, A, B, Q, R 1 , R 2 , R 3 , R 4 , Y 1 , Z, and a are as defined herein, compositions comprising an effective amount of a Phosphorus-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Phosphorus-Substituted Quinoxaline-Type Piperidine Compound.
• US9598447B2
  申请人：——

  公开号：US9598447B2

  公开（公告）日：2017-03-21