3-[2-(Cyclohex-1-EN-1-YL)ethyl]-N-[2-(diethylamino)ethyl]-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazoline-7-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 3-[2-(Cyclohex-1-EN-1-YL)ethyl]-N-[2-(diethylamino)ethyl]-4-oxo-2-sulfanylidene-1,2,3,4-tetrahydroquinazoline-7-carboxamide
• 英文别名: 3-[2-(cyclohexen-1-yl)ethyl]-N-[2-(diethylamino)ethyl]-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxamide
• 化学式: C₂₃H₃₂N₄O₂S
• mdl: MFCD02651670
• 分子量: 428.6
• InChiKey: TVNKNVNMCRFGRT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  30
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  96.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Antifungal agents and uses thereof
  申请人：University of Massachusetts

  公开号：US10350217B2

  公开（公告）日：2019-07-16

  Antimicrobial agents, compositions that include the agent(s) and use(s) thereof are provided. Also disclosed are screening assays for identifying antimicrobial agents.

  提供了抗菌剂、包括抗菌剂的组合物及其用途。还公开了用于鉴定抗菌剂的筛选测定法。
• ANTIFUNGAL AGENTS AND USES THEREOF
  申请人：University of Massachusetts

  公开号：US20140142107A1

  公开（公告）日：2014-05-22

  Antimicrobial agents, compositions that include the agent(s) and use(s) thereof are provided. Also disclosed are screening assays for identifying antimicrobial agents.
• SMALL MOLECULE INHIBITORS OF VIRAL PROTEIN INTERACTIONS WITH HUMAN T-RNA
  申请人：Sirga Advanced Biopharma, Inc.

  公开号：US20150190384A1

  公开（公告）日：2015-07-09

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  申请人：——

  公开号：US9648880B2

  公开（公告）日：2017-05-16
• US9775835B2
  申请人：——

  公开号：US9775835B2

  公开（公告）日：2017-10-03