3-[(2,3-Dioxo-1,4-dihydroquinoxalin-6-yl)sulfonyl]propanal

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 3-[(2,3-Dioxo-1,4-dihydroquinoxalin-6-yl)sulfonyl]propanal
• 英文别名: 3-[(2,3-dioxo-1,4-dihydroquinoxalin-6-yl)sulfonyl]propanal
• 化学式: C₁₁H₁₀N₂O₅S
• 分子量: 282.27
• InChiKey: YFKYIWKMNGMGEE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  118
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• MEDICAMENT FOR LIVER REGENERATION AND FOR TREATMENT OF LIVER FAILURE
  申请人：Zender Lars

  公开号：US20140141510A1

  公开（公告）日：2014-05-22

  The present invention relates to the use of a compound which inhibits the activity of MKK4 as a medicament for the treatment of a patient suffering from an impaired liver function, to the use of a compound as a medicament for the treatment of liver failure, including acute/fulminant or chronic liver failure and/or for increasing the regeneration of liver tissue in a patient.
• US9186381B2
  申请人：——

  公开号：US9186381B2

  公开（公告）日：2015-11-17