1-(2-Fluoroanilino)ethanol

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-(2-Fluoroanilino)ethanol
• 英文别名: 1-(2-fluoroanilino)ethanol
• 化学式: C₈H₁₀FNO
• 分子量: 155.17
• InChiKey: QYSPRTNOQQAQKF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  32.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL
  申请人：Stategics, Inc.

  公开号：EP2922548A2

  公开（公告）日：2015-09-30
• [EN] SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL<br/>[FR] COMPOSÉS TRIAZOLO-PYRIMIDINES SUBSTITUÉS POUR LA MODULATION DE LA PROLIFÉRATION, LA DIFFÉRENTIATION ET LA SURVIE CELLULAIRES
  申请人：STATEGICS INC

  公开号：WO2014081878A2

  公开（公告）日：2014-05-30

  Disclosed herein are erythropoietin-mimetic compounds of Formula I, which modulate the survival, function, or differentiation of, for example, kidney cells, neurons, erythroid cells, or other erythropoietin-responsive cells. The present invention also relates to compounds and methods that preferentially modulate cells expressing the tissue-protective erythropoietin receptor. The compounds of the invention are useful in preventing and treating diseases, such as anemia, organ injury, and diseases of the central nervous system, and as an adjunct to cellular treatments, such as stem cell therapies.