15,15,16-Triethyloctadecane-1,16-diamine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 15,15,16-Triethyloctadecane-1,16-diamine
• 英文别名: 15,15,16-triethyloctadecane-1,16-diamine
• 化学式: C₂₄H₅₂N₂
• 分子量: 368.7
• InChiKey: BZDYJTKNNLPTPQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.4
• 重原子数：
  26
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• PROSTACYLIN COMPOSITIONS AND METHODS FOR USING THE SAME
  申请人：Insmed Incorporated

  公开号：EP2925303A1

  公开（公告）日：2015-10-07
• [EN] PROSTACYLIN COMPOSITIONS AND METHODS FOR USING THE SAME<br/>[FR] COMPOSITIONS DE PROSTACYCLINE ET LEURS PROCÉDÉS D'UTILISATION
  申请人：INSMED INC

  公开号：WO2014085813A1

  公开（公告）日：2014-06-05

  The present invention relates to pharmaceutical compositions comprising a prostacyclin, a cationic compound, and a surfactant. Particulate compositions, including liposomal, solid nanoparticulate prostacyclin compositions, including treprostinil formulations comprising cationic compound and the surfactant are also described. The present invention also relates to a system comprising the pharmaceutical composition and an inhalation device. Methods for treating pulmonary hypertension and portopulmonary hypertension with the compositions and systems described herein are also provided.