Benzyl sulfate;trimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azanium

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Benzyl sulfate;trimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azanium
• 英文别名: benzyl sulfate;trimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azanium
• 化学式: C16H25NO6S
• 分子量: 359.4
• InChiKey: HGDRAVYKIHWQNT-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.48
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  101
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• POLYMER ENHANCEMENT OF ENZYMATIC ACTIVITY
  申请人：The Regents of the University of California

  公开号：US20150344924A1

  公开（公告）日：2015-12-03

  Provided herein are methods for enhancing enzymatic activity using certain polymers that may be optionally attached to an enzyme. The polymers may be thermally-responsive polymers, including poly N-isopropylacrylamide or poly N-isopropylmethacrylamide. The polymer may also be a copolymer with at least two different monomer residues. The monomer residues may have a structure of formula (I): wherein R 1 , R A and R B are as described herein. Examples of such monomer residues may include N-isopropylacrylamide (NIPAm) or N-isopropylmethacrylamide (NIPMa). The polymer may include additional monomer residues, such as aminooxy-bearing methacrylamide monomer residues that can be modified to vary the lower critical solution temperature (LCST) of the polymer.

  本文提供了一种利用某些聚合物增强酶活性的方法，这些聚合物可以选择性地附着在酶上。这些聚合物可以是热响应性聚合物，包括聚N-异丙基丙烯酰胺或聚N-异丙基甲基丙烯酰胺。该聚合物也可以是至少含有两种不同单体残基的共聚物。这些单体残基可能具有以下结构（I）的结构：其中R1，RA和RB如本文所述。此类单体残基的示例可能包括N-异丙基丙烯酰胺（NIPAm）或N-异丙基甲基丙烯酰胺（NIPMa）。该聚合物可能包括额外的单体残基，例如氨氧基甲基丙烯酰胺单体残基，可以被修改以改变聚合物的临界溶解温度（LCST）。
• METHOD FOR ENHANCEMENT OF ENZYMATIC ACTIVITY
  申请人：The Regents of the University of California

  公开号：EP2929042A1

  公开（公告）日：2015-10-14
• US9885071B2
  申请人：——

  公开号：US9885071B2

  公开（公告）日：2018-02-06
• [EN] METHOD FOR ENHANCEMENT OF ENZYMATIC ACTIVITY<br/>[FR] PROCÉDÉ VISANT À AMÉLIORER L'ACTIVITÉ ENZYMATIQUE
  申请人：UNIV CALIFORNIA

  公开号：WO2014089510A1

  公开（公告）日：2014-06-12

  Provided herein are methods for enhancing enzymatic activity using certain polymers that may be optionally attached to an enzyme. The polymers may be thermally-responsive polymers, including poly N-isopropylacrylamide or poly N-isopropylmethacrylamide. The polymer may also be a copolymer with at least two different monomer residues. The monomer residues may have a structure of formula (I) wherein R1 , RA and RB are as described herein. Examples of such monomer residues may include N-isopropylacrylamide (NIPAm) or N-isopropylmethacrylamide (NIPMa). The polymer may include additional monomer residues, such as aminooxy-bearing methacrylamide monomer residues that can be modified to vary the lower critical solution temperature (LCST) of the polymer.