4-[(4-Methylphenyl)methyl]-7-(3-phenylprop-1-ynyl)-[1,2,4]triazolo[4,3-a]quinazolin-5-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 4-[(4-Methylphenyl)methyl]-7-(3-phenylprop-1-ynyl)-[1,2,4]triazolo[4,3-a]quinazolin-5-one
• 英文别名: 4-[(4-methylphenyl)methyl]-7-(3-phenylprop-1-ynyl)-[1,2,4]triazolo[4,3-a]quinazolin-5-one
• 化学式: C₂₆H₂₀N₄O
• 分子量: 404.5
• InChiKey: NQDSAUARQMMPHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  31
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  51
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• ROLE OF PROTEOGLYCANS IN DRUG DEPENDENCE
  申请人：SANNA Pietro P.

  公开号：US20140173764A9

  公开（公告）日：2014-06-19

  The invention provides methods of preventing or treating drug addiction, or ameliorating the craving for an addictive drug, as well as compounds, peptides, and pharmaceutical compositions that may be used to prevent or treat drug addiction or ameliorate the craving for an addictive drug. The invention also provides methods for identifying agents that may be used to prevent or treat drug addiction, or ameliorate the craving for an addictive drug.