Benzo[a]phenazine-3,4-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: Benzo[a]phenazine-3,4-dione
• 英文别名: benzo[a]phenazine-3,4-dione
• 化学式: C₁₆H₈N₂O₂
• 分子量: 260.25
• InChiKey: HXBDLJHJJRXHNW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  20
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  59.9
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• COMPOUNDS AND METHODS FOR THE ENRICHMENT OF MUTATED NUCLEIC ACID FROM A MIXTURE
  申请人：Roche Diagnostics GmbH

  公开号：EP2935619A1

  公开（公告）日：2015-10-28
• METHODS FOR THE ENRICHMENT OF MUTATED NUCLEIC ACID FROM A MIXTURE
  申请人：Roche Diagnostics GmbH

  公开号：EP3074529A1

  公开（公告）日：2016-10-05
• Compounds and Methods for the Enrichment of Mutated Nucleic Acid from a Mixture
  申请人：Roche Molecular Systems, Inc.

  公开号：US20140308664A1

  公开（公告）日：2014-10-16

  The detection of the presence of rare somatic mutations from a biological sample is often challenging due to the simultaneous presence of a vast excess of wild-type DNA. The present invention describes novel compounds and methods that would allow the enrichment of mutant DNA by depleting amplifiable wild-type DNA.
• Methods for the Enrichment of Mutated Nucleic Acid from a Mixture
  申请人：Roche Molecular Systems, Inc.

  公开号：US20150147760A1

  公开（公告）日：2015-05-28

  The detection of the presence of rare somatic mutations from a biological sample is often challenging due to the simultaneous presence of a vast excess of wild-type DNA. The present invention describes methods that would allow the enrichment of mutant DNA by depleting amplifiable wild-type DNA.
• US9279146B2
  申请人：——

  公开号：US9279146B2

  公开（公告）日：2016-03-08