[(3R,5S,8R,9S,10S,13R,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: [(3R,5S,8R,9S,10S,13R,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate
• 化学式: C₁₉H₃₀O₄S
• 分子量: 354.5
• InChiKey: FHMBGAXGVUGLIR-PHFHYRSDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  72
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Molecularly imprinted polymer for selectively trapping odorous molecules
  申请人：L'ORÉAL

  公开号：US10772823B2

  公开（公告）日：2020-09-15

  The invention relates to the use of molecularly imprinted polymer(s) or MIPs, of odorous molecule(s), as deodorant agent in particular for selectively trapping molecules that are the cause of human body odour. More particularly by using MIPs which may be obtained via polymerization, preferably via radical polymerization, of a mixture of: i) optionally one or more polymerization initiator(s); ii) one or more functional monomer(s); iii) one or more crosslinking agent(s); and iv) one or more porogenic solvent(s); it being understood that the polymerization a) or b) is performed in the presence v) of one or more “templates” of target molecule(s) responsible for human body odour. Another subject of the invention concerns a process for preparing MIPs as defined previously, MIPs obtained via this process, and a cosmetic composition comprising at least one MIP as defined previously. Unexpectedly, it appears that the MIPs make it possible to specifically trap precursors of odorous molecules and odorous molecules that may be used in cosmetic formulations, especially those that are the cause of the unpleasant odour of sweat.

  本发明涉及气味分子的分子印迹聚合物或 MIPs 作为除臭剂的用途，特别是用于选择性地捕获导致人体气味的分子。更具体地说，MIPs 可通过以下混合物的聚合（最好是自由基聚合）获得：i) 一种或多种聚合引发剂；ii) 一种或多种功能性单体；iii) 一种或多种交联剂；iv) 一种或多种致孔溶剂。本发明的另一个主题涉及前文定义的 MIP 制备工艺、通过该工艺获得的 MIP 以及包含至少一种前文定义的 MIP 的化妆品组合物。令人意想不到的是，MIPs 似乎可以专门捕获气味分子的前体和可用于化妆品配方的气味分子，特别是那些导致难闻汗味的分子。
• Molecularly imprinted polymer of sol-gel type for selectively trapping odorous molecules
  申请人：L'ORÉAL

  公开号：US11246823B2

  公开（公告）日：2022-02-15

  The invention relates to the use of molecularly imprinted polymer(s) or MIPs, of odorous molecule(s), as deodorant agent in particular for selectively trapping molecules that are the cause of human body odour. More particularly by using MIPs which may be obtained via polymerization of “sol-gel” type; it being understood that the polymerization is performed in the presence v) of one or more “templates” of target molecule(s) responsible for human body odour. Another subject of the invention concerns a NI process for preparing MIPs as defined previously, MIPs obtained via this process, and a cosmetic composition comprising at least one MIP as defined previously. Unexpectedly, it appears that the MIPs make it possible to specifically trap precursors of odorous molecules and odorous molecules that may be used in cosmetic formulations, especially those that are the cause of the unpleasant odour of sweat.

  本发明涉及使用有气味分子的分子印迹聚合物或 MIPs 作为除臭剂，特别是选择性地捕获导致人体气味的分子。更特别的是，MIPs 可通过 "溶胶-凝胶 "型聚合反应获得；不言而喻，聚合反应是在一种或多种导致人体异味的目标分子 "模板 "存在的情况下进行的。本发明的另一个主题涉及一种用于制备如前定义的 MIP 的 NI 工艺、通过该工艺获得的 MIP 以及包含至少一种如前定义的 MIP 的化妆品组合物。出乎意料的是，MIPs 似乎可以特异性地捕获气味分子的前体和可用于化妆品配方的气味分子，特别是那些导致难闻汗味的分子。
• WATER-INSOLUBLE CYCLODEXTRIN POLYCONDENSATE; USES AS A CAPTURING AGENT
  申请人：L'Oréal

  公开号：EP2935340A1

  公开（公告）日：2015-10-28
• MOLECULARLY IMPRINTED POLYMER OF SOL-GEL TYPE FOR SELECTIVELY TRAPPING ODOROUS MOLECULES
  申请人：L'OREAL

  公开号：EP2938654B1

  公开（公告）日：2016-08-24
• MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES
  申请人：L'OREAL

  公开号：EP2938402A1

  公开（公告）日：2015-11-04