2-[2-[(6-Bromo-3-ethyl-1,3-benzothiazol-2-ylidene)methyl]but-1-enyl]-3-ethyl-6-methyl-1,3-benzothiazol-3-ium

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: 2-[2-[(6-Bromo-3-ethyl-1,3-benzothiazol-2-ylidene)methyl]but-1-enyl]-3-ethyl-6-methyl-1,3-benzothiazol-3-ium
• 英文别名: 2-[2-[(6-bromo-3-ethyl-1,3-benzothiazol-2-ylidene)methyl]but-1-enyl]-3-ethyl-6-methyl-1,3-benzothiazol-3-ium
• 化学式: C24H26BrN2S2+
• 分子量: 486.5
• InChiKey: MYSNGUXTCFNPSK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.4
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  60.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• METHODS AND COMPOUNDS TO INHIBIT ENVELOPED VIRUS RELEASE
  申请人：The Research Foundation for The State University of New York

  公开号：US20140179637A1

  公开（公告）日：2014-06-26

  A compound having an antiviral activity for inhibiting release of an enveloped virus from a cell is disclosed, including methods of inhibiting release of an enveloped virus from a cell. The antiviral activity of the compound includes inhibiting formation of an associative complex or disrupting formation of an associative complex. The associative complex comprises an L-domain motif of the enveloped virus and at least one cellular polypeptide, or fragment thereof, capable of binding the L-domain motif of the enveloped virus.