2-{[(2-fluorophenyl)carbonyl]amino}-N-(2-phenylethyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 环七噻吩
• 英文名称: 2-{[(2-fluorophenyl)carbonyl]amino}-N-(2-phenylethyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide
• 英文别名: 2-[(2-fluorobenzoyl)amino]-N-(2-phenylethyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide
• 化学式: C₂₅H₂₅FN₂O₂S
• mdl: MFCD02209535
• 分子量: 436.5
• InChiKey: CJHPHEFWWQBGPA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  31
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  86.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• DRUGS TO PREVENT HPV INFECTION
  申请人：Wisconsin Alumni Research Foundation

  公开号：US20150297602A1

  公开（公告）日：2015-10-22

  A method of inhibiting HPV virus infection is disclosed. In one embodiment, the method involves exposing a papillomavirus to an effective amount of a compound selected from the group consisting of Compound 13, Compound 14, and analogs of Compounds 13 and 14. In another embodiment, the method involves administering an inhibitor selected from the group consisting of Compound 13, Compound 14, and analogs of Compounds 13 and 14 to a susceptible tissue or cell.
• US9949980B2
  申请人：——

  公开号：US9949980B2

  公开（公告）日：2018-04-24