2-Hydroxyethyl 2-methylprop-2-enoate;trimethyl(2-phosphonooxyethyl)azanium;chloride

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-Hydroxyethyl 2-methylprop-2-enoate;trimethyl(2-phosphonooxyethyl)azanium;chloride
• 英文别名: 2-hydroxyethyl 2-methylprop-2-enoate;trimethyl(2-phosphonooxyethyl)azanium;chloride
• 化学式: C11H25ClNO7P
• 分子量: 349.74
• InChiKey: VJIIKPILZIUJGY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.1
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  113
• 氢给体数：
  3
• 氢受体数：
  8

文献信息

• BUTYRYLCHOLINESTERASE ZWITTERIONIC POLYMER CONJUGATES
  申请人：Kodiak Sciences Inc.

  公开号：US20160184445A1

  公开（公告）日：2016-06-30

  The present invention provides recombinant butyrylcholinesterase fusion proteins, including Fc fusion proteins and multi-armed high MW polymers containing hydrophilic groups conjugated to the fusion proteins, and methods of preparing such polymers.

  本发明提供了重组丁酰胆碱酯酶融合蛋白，包括Fc融合蛋白和含有与融合蛋白共轭的亲水基团的多臂高分子，并提供了制备这种高分子的方法。
• Low energy, cold process formulation aid
  申请人：Mateu Juan R.

  公开号：US10138374B2

  公开（公告）日：2018-11-27

  Provided are cold process formulation aids (CPFAs), methods for their manufacture, and personal care products made using them. CPFAs include (i) a polymer having an aliphatic backbone and a plurality of pendant groups thereon that are pendant ionic or ionizable groups, or pendant groups having at least one permanent dipole that includes an acid, alcohol, thiol, ester, amine, amide, imide, imine, or nitrile moiety, and (ii) a wax selected from natural waxes and synthetic waxes, wherein if the wax is not micronized and is not self-emulsifying, the ratio, by weight, of the non-micronized wax to the polymer having an aliphatic backbone is from about 60:40 to 80:20, and if the wax is a micronized wax or a self-emulsifying wax, the ratio, by weight, of wax to polymer backbone is 70:30 to 98:2.

  本文提供了冷加工配方助剂（CPFA）、其制造方法以及使用其制造的个人护理产品。CPFA 包括：(i) 具有脂肪族骨架和多个悬垂基团的聚合物，这些悬垂基团是悬垂离子基团或可电离基团，或具有至少一个永久偶极的悬垂基团，其中包括酸、醇、硫醇、酯、胺、酰胺、亚胺或腈分子；以及 (ii) 选自天然蜡和合成蜡的蜡、亚胺或腈分子，以及 (ii) 选自天然蜡和合成蜡的蜡，其中，如果蜡不是微粉化的，也不是自乳化的，则按重量计，非微粉化的蜡与具有脂肪族骨架的聚合物的比例约为 60：如果蜡是微粉化蜡或自乳化蜡，则蜡与聚合物骨架的重量比为 70:30 至 98:2。
• Butyrylcholinesterase zwitterionic polymer conjugates
  申请人：Kodiak Sciences Inc.

  公开号：US10363290B2

  公开（公告）日：2019-07-30

  The present invention provides recombinant butyrylcholinesterase fusion proteins, including Fc fusion proteins and multi-armed high MW polymers containing hydrophilic groups conjugated to the fusion proteins, and methods of preparing such polymers.

  本发明提供了重组丁酰胆碱酯酶融合蛋白，包括 Fc 融合蛋白和与融合蛋白共轭的含有亲水基团的多臂高分子量聚合物，以及制备此类聚合物的方法。
• Surface modified polymer compositions
  申请人：Lubrizol Advanced Materials, Inc.

  公开号：US10829606B2

  公开（公告）日：2020-11-10

  A surface-modified polymer composition formed from an oligomeric or polymeric additive and a base polymer is disclosed. The surface-modified polymer provides non-fouling and/or non-thrombogenic properties. The composition is particularly useful in articles and materials for medical applications.

  本发明公开了一种由低聚物或聚合物添加剂和基础聚合物形成的表面改性聚合物组合物。表面改性聚合物具有防污和/或防血栓形成的特性。这种组合物尤其适用于医疗用品和材料。
• Biocidally active polymer compositions
  申请人：Lubrizol Advanced Materials, Inc.

  公开号：US10827757B2

  公开（公告）日：2020-11-10

  A biocidally active polymer composition formed from an oligomeric or polymeric additive and a thermoplastic polyurethane polymer is disclosed. The biocidally active polymer may further include a non-fouling and/or non-thrombogenic polymer. The biocidally active polymer provides biocidally active properties, and may also provide non-fouling and/or non-thrombogenic properties. The composition is particularly useful in articles and materials for medical applications.

  本发明公开了一种由低聚物或聚合物添加剂和热塑性聚氨酯聚合物形成的生物防潮活性聚合物组合物。该生物防潮活性聚合物还可包括不结垢和/或不产生血栓的聚合物。生物防潮活性聚合物具有生物防潮活性特性，还可具有防污和/或非血栓形成特性。该组合物尤其适用于医疗用品和材料。