4-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]-2,2-dimethylpentanedioic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 蝶啶及其衍生物
• 英文名称: 4-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]-2,2-dimethylpentanedioic acid
• 化学式: C₂₁H₂₃N₇O₆
• 分子量: 469.5
• InChiKey: MRPPTQVMVFCFQJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  34
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  209
• 氢给体数：
  6
• 氢受体数：
  9

文献信息

• A METHOD FOR TREATING TUMOR BY USING RECOMBINANT INTERFERON WITH CHANGED SPATIAL CONFIGURATION
  申请人：Superlab Far East Limited

  公开号：EP2941264A2

  公开（公告）日：2015-11-11
• RECOMBINANT INTERFERON WITH CHANGED SPATIAL CONFIGURATION FOR USE IN THE TREATMENT OF MALIGNANT PLEURAL EFFUSION, MALIGNANT ASCITES, AND/OR MALIGNANT PERICARDIAL EFFUSION
  申请人：Superlab Far East Limited

  公开号：EP2941264B1

  公开（公告）日：2021-03-10
• METHOD FOR TREATING TUMOR BY USING RECOMBINANT INTERFERON WITH CHANGED SPATIAL CONFIGURATION
  申请人：SUPERLAB FAR EAST LIMITED

  公开号：US20180326012A1

  公开（公告）日：2018-11-15

  The present invention provides methods for treating tumors in subjects by using a recombinant interferon (rSIFN-co), and optionally, methods for treating solid tumors, such as lung cancer, among others, with or without prior surgery, and as a first line or second line monotherapy or in combination with one or more other anti-tumor therapies. The present invention further provides non-surgical methods for eliminating tumors or reducing tumor sizes in subjects, and/or preventing postoperative tumor recurrence and/or metastases in subjects by using the recombinant interferon (rSIFN-co) which comprises a unique spatial configuration, alone or in conjunction with radiotherapy, chemotherapy, and/or one or more anti-tumor drugs such as biological agents, targeted drugs, small molecules, Traditional Chinese Medicine (TCM) and the like.
• [EN] A METHOD FOR TREATING TUMOR BY USING RECOMBINANT INTERFERON WITH CHANGED SPATIAL CONFIGURATION<br/>[FR] PROCÉDÉ DE TRAITEMENT D'UNE TUMEUR EN UTILISANT UN INTERFÉRON RECOMBINANT AVEC UNE CONFIGURATION SPATIALE MODIFIÉE
  申请人：SUPERLAB FAR EAST LTD

  公开号：WO2014106459A2

  公开（公告）日：2014-07-10

  The present invention provides methods for treating tumors m subjects by using a recombinant interferon (rSIFN-coand optionally, methods for treating solid tumors, such as lung cancer among others with or without prior surgery and as a first line or second line monotherapy or in combination with one or more other anti-tumor therapies. The present invention further provides non-surgical methods for eliminating tumors or reducing tumor sizes in subjects, and/or preventing postoperative tumor recurrence and/or metastases in subjects by using the recombinant interferon (rSIFN-co) which comprises a unique spatial configuration, alone or in conjunction with radiotherapy, chemotherapy, and/or one or more anti-tumor drugs such as biological agents, targeted drugs, small molecules, Traditional Chinese Medicine (TCM) and the like.