2-(4-Methyl-1,3-thiazol-2-yl)-1,2-benzothiazol-3-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: 2-(4-Methyl-1,3-thiazol-2-yl)-1,2-benzothiazol-3-one
• 化学式: C₁₁H₈N₂OS₂
• 分子量: 248.3
• InChiKey: SIAIUZRYGLHACR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  86.7
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• COMBINED MODALITIES FOR NUCLEOSIDES AND/OR NADPH OXIDASE (NOX) INHIBITORS AS MYELOID-SPECIFIC ANTIVIRAL AGENTS
  申请人：Schinazi Raymond F.

  公开号：US20210060051A1

  公开（公告）日：2021-03-04

  The present invention is directed to compounds, compositions and methods for treating or preventing HIV and other viral infections, particularly where the virus is present in macrophages, microglia, and primary myeloid cells, and eliminating and/or treating infection in patients infected by these viruses.
• [EN] INHIBITORS OF NOX ENZYMES AND METHODS OF USE THEREOF<br/>[FR] INHIBITEURS D'ENZYMES NOX ET LEURS PROCÉDÉS D'UTILISATION
  申请人：UNIV EMORY

  公开号：WO2011062864A2

  公开（公告）日：2011-05-26

  Inhibitors of Nox enzymes, such as Noxl, Nox2, and Nox3, and methods of making and using such compounds are describe herein.