N-[2-(3,4-dihydroxyphenyl)ethyl]-2-sulfanylideneacetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: N-[2-(3,4-dihydroxyphenyl)ethyl]-2-sulfanylideneacetamide
• 化学式: C₁₀H₁₁NO₃S
• 分子量: 225.27
• InChiKey: RVXFHVNYMCDIFE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  102
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• COATING FOR SUBSTRATE
  申请人：Antoni Per

  公开号：US20140221522A1

  公开（公告）日：2014-08-07

  There is provided inter alia a substrate with a surface having a hydrophilic coating comprising a cross-linked copolymer of components A and B, and optional components C and D; wherein component A comprises one or more C 2 -C 16 hydrophilic monomers each bearing one or more alkene and/or alkyne groups; component B comprises one or more hydrophilic polymers each bearing two or more alkene and/or alkyne groups; component C, if present, comprises one or more beneficial agents each bearing one or more alkene or alkyne groups; and component D, if present, comprises one or more low molecular weight cross-linking agents each bearing two or more functional groups independently selected from thiol, alkene and alkyne groups; wherein the cross-linked copolymer is formed by radical polymerisation involving the alkene and/or alkyne groups of components A, B and C (if present) and involving the functional groups of component D (if present); wherein the hydrophilic coating optionally comprises component E which comprises one or more beneficial agents, wherein component E does not form a copolymer with components A, B, C (if present) and D (if present); and wherein the hydrophilic coating is covalently attached to the surface of the substrate.
• MEDICAL DEVICES COATED WITH POLYDOPAMINE AND ANTIBODIES
  申请人：OrbusNeich Medical PTE. LTD.

  公开号：US20210386916A1

  公开（公告）日：2021-12-16

  The present disclosure provides for a medical device or a substrate coated with polydopamine which is further linked to ligands such as antibodies and/or antibody fragments. The polydopamine coating and the ligands may be linked through a linker such as an organic polymer.
• US9272075B2
  申请人：——

  公开号：US9272075B2

  公开（公告）日：2016-03-01