[(1R,2S,4S,5'S,6S,7S,8R,9S,12R,13S,16S,18S)-5',7,9,16-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-piperidine]-1'-yl]methylidynephosphane

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: [(1R,2S,4S,5'S,6S,7S,8R,9S,12R,13S,16S,18S)-5',7,9,16-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-piperidine]-1'-yl]methylidynephosphane
• 化学式: C₂₈H₄₄NOP
• 分子量: 441.6
• InChiKey: MFYQJFOSIFQGFM-LWZYTUSYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.4
• 重原子数：
  31
• 可旋转键数：
  0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• METHODS FOR INHIBITING MUSCLE ATROPHY
  申请人：Adams Christopher M.

  公开号：US20140228333A1

  公开（公告）日：2014-08-14

  In one aspect, the invention relates to methods for treating muscle atrophy by providing to an animal in need thereof an effective amount of a compound. The compound can modulate the expression levels of multiple mRNA of a muscle atrophy signature. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• US9295664B2
  申请人：——

  公开号：US9295664B2

  公开（公告）日：2016-03-29