[(1R,2S,4S)-1,3-dihydroxy-4-[(S)-hydroxy(sulfooxy)methoxy]-1-methoxy-6-sulfooxyhexan-2-yl]sulfamic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫酸及其衍生物
• 英文名称: [(1R,2S,4S)-1,3-dihydroxy-4-[(S)-hydroxy(sulfooxy)methoxy]-1-methoxy-6-sulfooxyhexan-2-yl]sulfamic acid
• 化学式: C₈H₁₉NO₁₆S₃
• 分子量: 481.4
• InChiKey: WYJLLXDRGAZANO-GAMUGYIFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.7
• 重原子数：
  28
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  298
• 氢给体数：
  7
• 氢受体数：
  17

文献信息

• METHOD FOR FUNCTIONALIZING A POROUS MEMBRANE COVERING OF AN OPTICAL SENSOR TO FACILITATE COUPLING OF AN ANTITHROM-BOGENIC AGENT
  申请人：MEDTRONIC MINIMED, INC.

  公开号：US20140242710A1

  公开（公告）日：2014-08-28

  Methods of covalently attaching heparin to a membrane comprising plasma treating the membrane to produce an amino-functionalized membrane; and reacting the amino-functionalized membrane with heparin under conditions in which heparin becomes covalently attached to the amino-functionalized membrane, wherein said heparin is indirectly attached via a spacer to said amino-functionalized membrane and/or said heparin is attached from a single site in said heparin to a single site on said amino-functionalized membrane or to said spacer. Also disclosed are analyte sensors.