5-(1,1-Difluoropentyl)benzene-1,3-diol

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 5-(1,1-Difluoropentyl)benzene-1,3-diol
• 英文别名: 5-(1,1-difluoropentyl)benzene-1,3-diol
• 化学式: C₁₁H₁₄F₂O₂
• 分子量: 216.22
• InChiKey: VKGLEXDFUROZMW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• CANNABINERGIC NITRATE ESTERS AND RELATED ANALOGS
  申请人：Northeastern University

  公开号：US20160002195A1

  公开（公告）日：2016-01-07

  The present technology relates to novel cannabinergic nitrate esters and related analogs, process of preparation, pharmaceutical compositions and their methods of use as medicaments, pharmacological tools and/or biomarkers. The novel cannabinergic nitrate ester compounds provide medicaments useful in treating a variety of diseases and medical disorders.

  本技术涉及新型大麻素硝酸酯及其类似物、制备方法、制药组合物及其作为药物、药理工具和/或生物标志物的使用方法。这些新型大麻素硝酸酯化合物提供了治疗各种疾病和医学障碍的有用药物。
• CANNABIDIOL DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF
  申请人：Chengdu Baiyu Pharmaceutical Co., Ltd.

  公开号：EP4089084A1

  公开（公告）日：2022-11-16

  The present invention relates to cannabidiol derivatives and medical use thereof, in particular to pyrimidine derivatives represented by general formula (I), or stereoisomers, solvates, metabolites, prodrugs, pharmaceutically acceptable salts or cocrystals thereof, wherein the definitions of substituents in general formula (I) are the same as those in the description

  本发明涉及大麻二酚衍生物及其医疗用途，特别是通式（I）代表的嘧啶衍生物，或其立体异构体、溶解物、代谢物、原药、药学上可接受的盐或共晶体，其中通式（I）中取代基的定义与描述中的相同
• Cannabinergic nitrate esters and related analogs
  申请人：Northeastern University

  公开号：US10221164B2

  公开（公告）日：2019-03-05

  The present technology relates to novel cannabinergic nitrate esters and related analogs, process of preparation, pharmaceutical compositions and their methods of use as medicaments, pharmacological tools and/or biomarkers. The novel cannabinergic nitrate ester compounds provide medicaments useful in treating a variety of diseases and medical disorders.

  本技术涉及新型大麻素能硝酸酯和相关类似物、制备工艺、药物组合物及其作为药物、药理学工具和/或生物标记物的使用方法。新型大麻素能硝酸酯化合物可提供治疗各种疾病和医学紊乱的药物。
• [EN] CANNABIDIOL DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF<br/>[FR] DÉRIVÉ CANNABIDIOL ET SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION MÉDICALE<br/>[ZH] 大麻二酚衍生物及其制备方法和在医药上的应用
  申请人：CHENGDU BAIYU PHARMACEUTICAL CO LTD

  公开号：WO2021139741A1

  公开（公告）日：2021-07-15

  大麻二酚衍生物及其在医药上的应用，具体而言涉及如通式(I)所示的嘧啶衍生物，或者其立体异构体、溶剂化物、代谢产物、前药、药学上可接受的盐或共晶，其中，通式(I)中各取代基的定义与说明书的定义相同。
• Cannabinergic Nitrate Esters And Related Analogs
  申请人：Northeastern University

  公开号：US20170210728A1

  公开（公告）日：2017-07-27

  The present technology relates to novel cannabinergic nitrate esters and related analogs, process of preparation, pharmaceutical compositions and their methods of use as medicaments, pharmacological tools and/or biomarkers. The novel cannabinergic nitrate ester compounds provide medicaments useful in treating a variety of diseases and medical disorders.