1,2,2-Trimethyl-3-propan-2-ylaziridine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,2,2-Trimethyl-3-propan-2-ylaziridine
• 英文别名: 1,2,2-trimethyl-3-propan-2-ylaziridine
• 化学式: C₈H₁₇N
• 分子量: 127.23
• InChiKey: VGQZMZYHEVENFT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• USING SORTASES TO INSTALL CLICK CHEMISTRY HANDLES FOR PROTEIN LIGATION
  申请人：Ploegh Hidde L

  公开号：US20140249296A1

  公开（公告）日：2014-09-04

  Methods and reagents for the installation of click chemistry handles on target proteins are provided, as well as modified proteins comprising click chemistry handles. Further, chimeric proteins, for example, bi-specific antibodies, that comprise two proteins conjugated via click chemistry, as well as methods for their generation and use are disclosed herein.
• SORTASE-MODIFIED VHH DOMAINS AND USES THEREOF
  申请人：Whitehead Institute for Biomedical Research

  公开号：US20150086576A1

  公开（公告）日：2015-03-26

  In some aspects, polypeptides comprising single domain antibodies and methods of identifying single domain antibodies are provided. In some embodiments polypeptides comprising a single domain antibody and a sortase recognition sequence, are provided. In some aspects, products and methods of use in modulating the immune system, e.g., modulating an immune response, are provided.
• US9751945B2
  申请人：——

  公开号：US9751945B2

  公开（公告）日：2017-09-05