2-Butoxy-6-propan-2-ylcyclohepta-2,4,6-trien-1-one

• 分子结构分类: 有机化合物 - 碳氢化合物衍生物 - 环庚三烯酮
• 英文名称: 2-Butoxy-6-propan-2-ylcyclohepta-2,4,6-trien-1-one
• 英文别名: 2-butoxy-6-propan-2-ylcyclohepta-2,4,6-trien-1-one
• 化学式: C₁₄H₂₀O₂
• 分子量: 220.31
• InChiKey: VTXQXSSFNUOXQS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• THERMALLY-ACTIVATED SELF-IMMOLATIVE MATERIALS
  申请人：UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION

  公开号：US20150368403A1

  公开（公告）日：2015-12-24

  A polymer including a self-immolative polymer segment and a thermally-activated trigger moiety is described. The self-immolative polymer segment includes a head end, a tail end, and a plurality of repeating units. The trigger moiety includes a cycloaddition adduct that is covalently coupled to the head end of the self-immolative polymer segment. When the polymer is exposed to an activation temperature, the cycloaddition adduct undergoes retro-cycloaddition to release the self-immolative polymer segment. The self-immolative polymer segment then decomposes to sequentially release repeating units in a head-to-tail direction.
• US9580553B2
  申请人：——

  公开号：US9580553B2

  公开（公告）日：2017-02-28
• [EN] THERMALLY-ACTIVATED SELF-IMMOLATIVE MATERIALS<br/>[FR] MATÉRIAUX AUTO-IMMOLATEURS THERMO-ACTIVÉS
  申请人：UNIV WASHINGTON CT COMMERCIALI

  公开号：WO2014133620A2

  公开（公告）日：2014-09-04

  A polymer including a self-immolative polymer segment and a thermally-activated trigger moiety is described. The self-immolative polymer segment includes a head end, a tail end, and a plurality of repeating units. The trigger moiety includes a cycloaddition adduct that is covalently coupled to the head end of the self-immolative polymer segment. When the polymer is exposed to an activation temperature, the cycloaddition adduct undergoes retro-cycloaddition to release the self-immolative polymer segment. The self-immolative polymer segment then decomposes to sequentially release repeating units in a head-to-tail direction.