Ethoxyethane;trimethyl(2-phosphonooxyethyl)azanium

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Ethoxyethane;trimethyl(2-phosphonooxyethyl)azanium
• 英文别名: ethoxyethane;trimethyl(2-phosphonooxyethyl)azanium
• 化学式: C9H25NO5P+
• 分子量: 258.27
• InChiKey: GJIRDVRDRBKUHH-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  0.84
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  76
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Lipidomics of familial longevity
  申请人：Academisch Ziekenhuis Leiden h.o.d.n. LUMC

  公开号：EP2778686B1

  公开（公告）日：2016-07-27
• US20140274956A1
  申请人：——

  公开号：US20140274956A1

  公开（公告）日：2014-09-18
• LIPID BIOMARKERS OF HEALTHY AGEING
  申请人：NESTEC S.A.

  公开号：US20160245786A1

  公开（公告）日：2016-08-25

  In one aspect there is provided a method for predicting a risk of unhealthy ageing in a subject, comprising: (a) determining a level of two or more lipid biomarkers in a sample from the subject, wherein the biomarkers are selected from two or more of the following groups: (i) a triacylglycerol (TAG) from TAG (46:5) to TAG (54:3); (ii) an ether phosphatidylcholine (PC-O) from PC-O(28:0) to PC-O(38:6); (iii) a sphingomyelin (SM) from SM (33:1) to SM(50:1); (iv) a phosphatidylcholine (PC) from PC (32:1) to PC (40:5); (v) a phosphatidylinositol (PI) from PI (36:1) to PI (38:3); (vi) a phosphatidylethanolamine (PE) from PE (36:2) to PE (38:4); and (b) comparing the levels of the biomarkers in the sample to reference values; wherein the levels of the biomarkers in the sample compared to the reference values are indicative of the risk of unhealthy ageing in the subject.