6-bromo-2,4-dimethyl-4H-1,2-benzoxazin-3-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 英文名称: 6-bromo-2,4-dimethyl-4H-1,2-benzoxazin-3-one
• 化学式: C₁₀H₁₀BrNO₂
• 分子量: 256.1
• InChiKey: OWELRRVDPOOZFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] DEUTERIUM-ENRICHED TANAPROGET AND PROCESSES FOR ITS PREPARATION<br/>[FR] TANAPROGET ENRICHI EN DEUTÉRIUM ET PROCÉDÉS DE PRÉPARATION ASSOCIÉS
  申请人：TEVA WOMENS HEALTH INC

  公开号：WO2014143617A1

  公开（公告）日：2014-09-18

  The present invention provides a deuterium enriched Tanaproget compound, isomer thereof, or a pharmaceutically acceptable salt thereof, including the following compound. These compounds may be utilized in reference standards and compositions. Also provided are methods of contraception, hormone replacement therapy, and treating and/or preventing uterine fibroids, dysfunctional bleeding, uterine leiomyomata, endometriosis, polycystic ovary syndrome, and benign and malignant neoplastic disease using these compounds.