[(Z)-hexadec-7-enyl]cyanamide

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: [(Z)-hexadec-7-enyl]cyanamide
• 化学式: C₁₇H₃₂N₂
• 分子量: 264.4
• InChiKey: XRKNOKUYVLALTM-KTKRTIGZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  19
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  35.8
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] SUBSTITUTED 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS<br/>[FR] COMPOSÉS HÉTÉROARYLES BICYCLIQUES SUBSTITUÉS CONDENSÉS EN 6,5
  申请人：EPIZYME INC

  公开号：WO2014144747A1

  公开（公告）日：2014-09-18

  The present invention relates to azole bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

  本发明涉及唑类双环杂环芳基化合物。本发明还涉及含有这些化合物的药物组合物，以及通过向需要的受试者投与这些化合物和药物组合物来治疗癌症的方法。本发明还涉及利用这些化合物进行研究或其他非治疗目的的用途。
• Substituted Benzene Compounds
  申请人：Epizyme, Inc.

  公开号：US20140315945A1

  公开（公告）日：2014-10-23

  The present invention relates to azole compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

  本发明涉及唑类化合物。本发明还涉及含有这些化合物的药物组合物以及通过向需要的受试者投予这些化合物和药物组合物来治疗癌症的方法。本发明还涉及将这些化合物用于研究或其他非治疗目的的用途。
• Substituted 6,5-Fused Bicyclic Heteroaryl Compounds
  申请人：Epizyme, Inc.

  公开号：US20140296283A1

  公开（公告）日：2014-10-02

  The present invention relates to azole bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

  本发明涉及杂环双环杂芳基化合物。本发明还涉及含有这些化合物的药物组合物以及通过将这些化合物和药物组合物用于需要的受试者治疗癌症的方法。本发明还涉及将这些化合物用于研究或其他非治疗目的的使用。
• Substituted 6, 5-Fused Bicyclic Heteroaryl Compounds
  申请人：EPIZYME, INC.

  公开号：US20150246916A1

  公开（公告）日：2015-09-03

  The present invention relates to azole bicyclic heteroaryl compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

  本发明涉及杂环双环杂芳烃化合物。本发明还涉及含有这些化合物的药物组合物以及通过将这些化合物和药物组合物用于需要的受试者治疗癌症的方法。本发明还涉及将这些化合物用于研究或其他非治疗目的的用途。
• SUBSTITUTED BENZENE COMPOUNDS
  申请人：Epizyme, Inc.

  公开号：US20160244464A1

  公开（公告）日：2016-08-25

  The present invention relates to azole compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.

  本发明涉及唑类化合物。本发明还涉及含有这些化合物的药物组合物以及通过向需要此类化合物和药物组合物的受试者施用这些化合物和药物组合物来治疗癌症的方法。本发明还涉及将这种化合物用于研究或其他非治疗目的的用途。