4,5-Dimethyl-2-oxopyrrole-3-carbonitrile

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 4,5-Dimethyl-2-oxopyrrole-3-carbonitrile
• 英文别名: 4,5-dimethyl-2-oxopyrrole-3-carbonitrile
• 化学式: C₇H₆N₂O
• 分子量: 134.14
• InChiKey: CFKIUROOAKDINZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  53.2
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• TWO-PHOTON FLUORESCENT PROBE USING NAPHTHALENE AS MATRIX AND PREPARATION METHOD AND USE THEREOF
  申请人：Dalian University Of Technology

  公开号：EP2778161B1

  公开（公告）日：2015-05-06
• NAPHTHALENE-BASED TWO-PHOTON FLUORESCENT PROBES, PREPARATION METHOD AND USE THEREOF
  申请人：Peng Xiaojun

  公开号：US20150079625A1

  公开（公告）日：2015-03-19

  The present invention provides a novel category of naphthalene-based two-photon fluorescent probes having a general formula I, wherein: X is selected from the X 1 , X 2 , X 3 and X 4 ; The mentioned two-photon fluorescent probes have a low fluorescence background in the non-tumor cells and tissues, and have a strong and specific fluorescent signal in the tumor cells and tissues. These probes have a certain level of water-solubility, while having good membrane permeability. In addition, they have a bigger effective two-photon absorption cross section. The compounds of the present invention also have a lower biotoxicity, phototoxicity and photobleaching. There is sufficient difference between the spectral range thereof and that of a biological sample.
• US9182350B2
  申请人：——

  公开号：US9182350B2

  公开（公告）日：2015-11-10