1-N'-ethyl-1-N,1-N'-dimethylethane-1,1-diamine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-N'-ethyl-1-N,1-N'-dimethylethane-1,1-diamine
• 化学式: C₆H₁₆N₂
• 分子量: 116.2
• InChiKey: DYMALLBXOIZJPL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  15.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS<br/>[FR] CYCLOALKYLNITRILE PYRAZOLOPYRIDONES UTILISÉES COMME INHIBITEURS DE LA JANUS KINASE
  申请人：MERCK SHARP & DOHME

  公开号：WO2014146490A1

  公开（公告）日：2014-09-25

  Compounds of formula I are provided, which are JAK inhibitors and are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

  公式I的化合物被提供，这些化合物是JAK抑制剂，对于治疗JAK介导的疾病，如类风湿性关节炎、哮喘、慢性阻塞性肺病（COPD）和癌症等疾病是有用的。
• CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS
  申请人：Merck Sharp & Dohme Corp.

  公开号：EP2976340A1

  公开（公告）日：2016-01-27
• 1,3,4-OXADIAZOLE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
  申请人：Chong Kun Dang Pharmaceutical Corp.

  公开号：EP3331864B1

  公开（公告）日：2021-11-03
• ASSOCIATIVE POLYMERS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
  申请人：CALIFORNIA INSTITUTE OF TECHNOLOGY

  公开号：US20220145012A1

  公开（公告）日：2022-05-12

  Described herein are associative polymers capable of controlling a physical and/or chemical property of non-polar compositions and related compositions, methods and systems. Associative polymers herein described have a non-polar backbone and functional groups presented at ends of the non-polar backbone, with a number of the functional groups presented at the ends of the non-polar backbone formed by associative functional groups capable of undergoing an associative interaction with another associative functional group with an association constant (k) such that the strength of each associative interaction is less than the strength of a covalent bond between atoms and in particular less than the strength of a covalent bond between backbone atoms.
• [EN] LANTHANIDE AND LANTHANIDE-LIKE TRANSITION METAL COMPLEXES<br/>[FR] COMPLEXES DE MÉTAUX DE TRANSITION LANTHANIDIQUES OU DE TYPE LANTHANIDIQUE
  申请人：[en]MERCK PATENT GMBH

  公开号：WO2022106508A1

  公开（公告）日：2022-05-27

  The disclosed and claimed subject matter provides precursors having at least one tethered cyclopentadienyl ligand ("Cp ligand"), at least one amidinate ligand ("Ad ligand") and a lanthanide and/or lanthanide-like transition metal ("M") of the general formulae (i) (Cp ligand)2- M-(Ad ligand) or (ii) (Cp ligand)-M-(Ad ligand)2.