Murexine | 20284-40-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Murexine
• 英文别名: 2-[(E)-3-(1H-imidazol-5-yl)prop-2-enoyl]oxyethyl-trimethylazanium
• CAS: 20284-40-6
• 化学式: C11H18N3O2+
• 分子量: 224.28
• InChiKey: XDPGNNXEHPAHCJ-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  55
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• FERMENTED FOOD EXTRACT COMPOSITION
  申请人：Shinshu University

  公开号：US20170182108A1

  公开（公告）日：2017-06-29

  Provided is a fermented food extract that has a blood pressure-lowering action and is useful as a functional health food or pharmaceutical composition. This fermented food extract is obtained by: subjecting a fermented food, preferably a fermented fagopyrum esculentum lyophilisate, to acetone extraction; eluting the fermented fagopyrum esculentum acetone extract using a solid phase extract cartridge filled with a resin to which a phenyl group is bonded, with formic acid-containing water used as an eluent; and fractionating and purifying the eluate using a column (PFP column) filled with a carrier to which a pentafluorophenyl group is bonded, with formic acid/methanol-containing water used as a mobile phase. This functional health food or pharmaceutical composition contains said extract or at least a part thereof as an active ingredient.

  提供的是一种具有降血压作用并可用作功能性健康食品或药用组合物的发酵食品提取物。该发酵食品提取物的获取方法包括：将发酵食品（最好是发酵荞麦冻干物）经过丙酮提取；使用装有与苯基结合的树脂的固相萃取柱来洗脱发酵荞麦丙酮提取物，使用含甲酸的水作为洗脱剂；并使用装有与五氟苯基结合的载体的柱（PFP柱）来分馏和纯化洗脱物，使用含甲酸/甲醇的水作为流动相。这种功能性健康食品或药用组合物含有所述提取物或其至少一部分作为活性成分。
• Anti-Inflammatory and Anti-Allergy Extracts from Nettle
  申请人：Alberte Randall S.

  公开号：US20100009927A1

  公开（公告）日：2010-01-14

  The present invention relates in part to nettle extracts that are useful for treating or preventing seasonal allergies, allergic rhinitis, and other inflammatory conditions.
• Extracts of Curcuma and Methods of Use Thereof
  申请人：Alberte Randall S.

  公开号：US20100098788A1

  公开（公告）日：2010-04-22

  The present invention relates in part to turmeric extracts that are useful for treating or preventing neurodegenerative disorders. Another aspect of the invention relates in part to turmeric extracts that are useful for treating or preventing inflammatory disorders. In some embodiments, the extracts comprise at least one compound selected from the group consisting of 25 to 500 μg bamosamine, 25 to 750 μg echinaxanthol, 100 to 3,000 μg bisdemethoxycurcumin, 50 to 500 μg daphniyunnine E and 500 to 75,000 μg curcumin per 100 mg of extract. Another aspect of the invention relates to pharmaceutical compositions comprising the aforementioned extracts. Another aspect of the invention relates to methods of treating or preventing neurodegenerative disorders comprising administering to a subject in need thereof an effective amount of the aforementioned extracts or compositions. Another aspect of the invention relates to methods of making the aforementioned extracts.
• CHOLINE ESTER-CONTAINING COMPOSITION FOR ORAL INGESTION
  申请人：Shinshu University

  公开号：US20220030896A2

  公开（公告）日：2022-02-03

  The object of the present invention is to provide a composition having a blood pressure-lowering effect and/or an anti-stress effect, wherein an active ingredient of a choline ester such as acetylcholine, and the like, can be easily administered to humans by the oral pathway. Consequently, the object of the present invention is to provide a novel composition for oral ingestion having a blood pressure-lowering effect and a vasodilatory effect, wherein a choline ester such as acetylcholine, and the like, can be easily administered to humans by the oral pathway, and to provide food which is a useful supply source therefore.
• [EN] ANTI-INFLAMMATORY AND ANTI-ALLERGY EXTRACTS FROM NETTLE<br/>[FR] EXTRAITS D'ORTIE ANTI-INFLAMMATOIRES ET ANTIALLERGIQUES
  申请人：HERBALSCIENCE GROUP LLC

  公开号：WO2010009091A2

  公开（公告）日：2010-01-21

  The present invention relates in part to nettle extracts that are useful for treating or preventing seasonal allergies, allergic rhinitis, and other inflammatory conditions.