2-(Dibutylamino)ethanol hydrochloride | 99868-60-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-(Dibutylamino)ethanol hydrochloride
• 英文别名: 2-(dibutylamino)ethanol;hydrochloride
• CAS: 99868-60-7
• 化学式: C₁₀H₂₃NO*ClH
• 分子量: 209.76
• InChiKey: FPLFAWOYBWHAIW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  23.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  苯胺 、 2-(Dibutylamino)ethanol hydrochloride 在 ruthenium trichloride 、 三苯基膦 tin(ll) chloride 作用下， 以 1,4-二氧六环 、 水 为溶剂， 反应 20.0h， 以17%的产率得到吲哚
  参考文献：
  名称：

  钌催化的苯胺与链烷醇氯化铵的杂环化反应生成吲哚

  摘要：

  在催化量的钌催化剂和SnCl 2 ·2H 2 O的存在下，苯胺在水性介质（H 2 O-二恶烷）中在180°C下与链烷醇氯化铵反应，以中等至良好的收率得到相应的吲哚。特别是，当使用氯化三异丙基丙铵与苯胺反应时，区域选择性地形成2-甲基吲哚。的SnCl存在2 ·2H 2 O为必需的有效形成吲哚。针对该催化过程，提出了一种涉及链烷醇基团从链烷醇胺转移至苯胺，苯胺被苯胺链烷醇进行N-烷基化以及1,2-二苯胺基烷烃的杂环化反应的反应途径。

  DOI：

  10.1016/s0040-4020(01)00202-2

文献信息

• POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYMERIZABLE COMPOSITION CONTAINING THE CATALYST, POLYTHIOURETHANE RESIN OBTAINED FROM THE COMPOSITION, AND METHOD FOR PRODUCING THE RESIN
  申请人：Mitsui Chemicals, Inc.

  公开号：EP2065414A1

  公开（公告）日：2009-06-03

  By using an amine hydrochloride represented by the formula (1) as a catalyst, a polythiourethane resin which is suitably used for a transparent resin for optical use, can be obtained without using an organotin compound which has been conventionally used as a catalyst for polythiourethane resins and without being affected by the acidity of an additive: wherein R1, R2 and R3 independently represent a monovalent or higher valent linear aliphatic, branched aliphatic, cyclic aliphatic or aromatic organic residue which may have a hydroxyl group or an amino group; and R1, R2 and R3 may be arbitrarily bonded to each other to form a ring.

  使用由式（1）表示的胺盐酸盐作为催化剂，可以获得一种适合用于光学用透明树脂 的聚硫氨酸树脂，而无需使用传统上用作聚硫氨酸树脂催化剂的有机锡化合物，也不会 受到添加剂酸性的影响： 其中 R1、R2 和 R3 独立地代表一价或更高价的线性脂肪族、支链脂肪族、环状脂肪族或芳香族有机残基，可带有羟基或氨基；R1、R2 和 R3 可任意地相互键合以形成环。
• POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYMERIZABLE COMPOSITION CONTAINING THE SAME, POLYTHIOURETHANE RESIN OBTAINED FROM THE COMPOSITION, AND PROCESS FOR PRODUCING THE RESIN
  申请人：Kawato Nobuo

  公开号：US20100029890A1

  公开（公告）日：2010-02-04

  By using an amine hydrochloride represented by the formula (1) as a catalyst, a polythiourethane resin which is suitably used for a transparent resin for optical use, can be obtained without using an organotin compound which has been conventionally used as a catalyst for polythiourethane resins and without being affected by the acidity of an additive: wherein R 1 , R 2 and R 3 independently represent a monovalent or higher valent linear aliphatic, branched aliphatic, cyclic aliphatic or aromatic organic residue which may have a hydroxyl group or an amino group; and R 1 , R 2 and R 3 may be arbitrarily bonded to each other to form a ring.
• US8586695B2
  申请人：——

  公开号：US8586695B2

  公开（公告）日：2013-11-19
• Ruthenium-catalyzed heteroannulation of anilines with alkanolammonium chlorides leading to indoles
  作者：Chan Sik Cho、Jin Hwang Kim、Tae-Jeong Kim、Sang Chul Shim

  DOI：10.1016/s0040-4020(01)00202-2

  日期：2001.4

  Anilines react with alkanolammonium chlorides in an aqueous medium (H2O–dioxane) at 180°C in the presence of a catalytic amount of a ruthenium catalyst together with SnCl2·2H2O to afford the corresponding indoles in moderate to good yields. Especially, when triisopropanolammonium chloride is employed to react with anilines, 2-methylindoles are formed regioselectively. The presence of SnCl2·2H2O is

  在催化量的钌催化剂和SnCl 2 ·2H 2 O的存在下，苯胺在水性介质（H 2 O-二恶烷）中在180°C下与链烷醇氯化铵反应，以中等至良好的收率得到相应的吲哚。特别是，当使用氯化三异丙基丙铵与苯胺反应时，区域选择性地形成2-甲基吲哚。的SnCl存在2 ·2H 2 O为必需的有效形成吲哚。针对该催化过程，提出了一种涉及链烷醇基团从链烷醇胺转移至苯胺，苯胺被苯胺链烷醇进行N-烷基化以及1,2-二苯胺基烷烃的杂环化反应的反应途径。