sec-butyl-quinazolin-4-yl-amine | 22754-08-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: sec-butyl-quinazolin-4-yl-amine
• 英文别名: N-(butan-2-yl)quinazolin-4-amine；N-butan-2-ylquinazolin-4-amine
• CAS: 22754-08-1
• 化学式: C₁₂H₁₅N₃
• mdl: MFCD04210485
• 分子量: 201.271
• InChiKey: DFOKBVJVIWIVLK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  37.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Identification of CDKI pathway inhibitors
  申请人：Chang Bey-Dih

  公开号：US20080033000A1

  公开（公告）日：2008-02-07

  The invention relates to the inhibition of the Cyclin-Dependent Kinase Inhibitor (CDKI) pathway. More particularly, the invention relates to methods for inhibiting the CDKI pathway for studies of and intervention in senescence-related and other CDKI-related diseases.
• CDKI Pathway inhibitors and uses thereof to regulate expression to TAU protein
  申请人：Porter Donald

  公开号：US20100190807A1

  公开（公告）日：2010-07-29

  The invention relates to the inhibition of the Cyclin-Dependent Kinase Inhibitor (CDKI) pathway. More particularly, the invention relates to methods for inhibiting increases in MAPT expression induced by the CDKI pathway for studies of and intervention in senescence-related and other CDKI-related diseases.