6-二乙基氨基-2,3-二氢酞嗪-1,4-二酮 | 29415-71-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 中文名称: 6-二乙基氨基-2,3-二氢酞嗪-1,4-二酮
• 英文名称: 4-diethylaminophthalhydrazide
• 英文别名: 4-Diaethylamino-phthalhydrazid；Diethylisoluminol；4-Diaethylamino-phthalsaeurehydrazid；6-diethylamino-2,3-dihydro-phthalazine-1,4-dione；6-(Diethylamino)-2,3-dihydrophthalazine-1,4-dione
• CAS: 29415-71-2
• 化学式: C₁₂H₁₅N₃O₂
• mdl: MFCD00157919
• 分子量: 233.27
• InChiKey: WNYLSNZNCJLARI-UHFFFAOYSA-N

物化性质

• 密度：
  1.212±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  61.4
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 危险等级：
  IRRITANT

反应信息

• 作为反应物：
  描述：

  6-二乙基氨基-2,3-二氢酞嗪-1,4-二酮 在 氢氧化钾 、 铜 、 双氧水 作用下， 以 水 为溶剂， 生成
  参考文献：
  名称：

  Pyatnitskii, I. V.; Zaporozhets, O. A.; Dubovenko, L. I., Journal of General Chemistry of the USSR, 1988, vol. 58, # 5, p. 997 - 1003

  摘要：

  DOI：

文献信息

• POLYMERIZABLE CHEMILUMINESCENT COMPOUNDS
  申请人：Ippoliti Joseph Thomas

  公开号：US20080233601A1

  公开（公告）日：2008-09-25

  Disclosed are compounds having the formula: wherein R 1 is selected from the group consisting of hydrogen, C 1 -C 6 alkyl, amino, N-C 1 -C 6 -alkylamino, and N,N—C 1 -C 6 -dialkylamino; and ring “A” is selected from the group consisting of unsubstituted or substituted C 4 -C 8 -cycloalkenyl, unsubstituted or substituted bicyclo [2,2,1]alkenyl, and unsubstituted or substituted bicyclo [2,2,2]alkenyl, unsubstituted phenyl, and phenyl substituted with a moiety selected from the group consisting of C 3 -C 6 -alkenyl, acryl, acryl-C 1 -C 6 alkyl, acrylamido, and acrylamido-C 1 -C 6 alkyl; polymers made from these compounds, and ELISAs that use the compounds and polymers as a chemiluminescent detection label.

  揭示了具有以下结构的化合物：其中R1选择自氢、C1-C6烷基、氨基、N-C1-C6-烷基氨基和N,N-二(C1-C6)烷基氨基的基团中的一种；环“A”选择自未取代或取代的C4-C8环烯基、未取代或取代的双环[2,2,1]烯基和未取代或取代的双环[2,2,2]烯基、未取代苯基和被选自C3-C6烯基、丙烯酰、丙烯酰-C1-C6烷基、丙烯酰胺和丙烯酰胺-C1-C6烷基的基团取代的苯基；由这些化合物制成的聚合物，以及使用这些化合物和聚合物作为化学发光检测标记的ELISA。
• Microchemiluminescent assay system
  申请人：Kiel, Jonathan L

  公开号：EP0175577A2

  公开（公告）日：1986-03-26

  A composition for use in a thermochemiluminescent assay. The composition includes a heme protein, a luminescer such as luminol, and serum albumin, the luminescer being non-covalently bonded to serum albumin. The composition may be used in a thermochemiluminescent for the ligant of a specific binding pair in which the composition is contacted with a fluid sample suspected of containing the antiligand of the specific binding pair and the subsequent light-emitting reaction is quantified. The specific binding light-emitting reaction is quantified. The specific binding pair can be, for instance, an enzyme and the substrate for which it is specific. The composition and the assay can be modified to detect ionizing radiation, peroxidative injury to cells, heat or a particular cell type.

  一种用于热化学发光检测的组合物。 该组合物包括血红素蛋白、发光剂（如发光酚）和血清白蛋白，发光剂与血清白蛋白非共价键合。 该组合物可用于特异性结合配对的配体的热化学发光，在该热化学发光中，组合物与疑似含有特异性结合配对的抗配体的流体样品接触，随后的发光反应被量化。 特异性结合发光反应被量化。 特异性结合配对可以是酶和它所特异的底物等。 该组合物和检测方法可以改进，以检测电离辐射、细胞过氧化损伤、热或特定细胞类型。
• PROCEDE POUR DETECTER ET LOCALISER DES TRACES DE SANG ET COMPOSE POUR DETECTER DES TRACES DE SANG
  申请人：Roc Import

  公开号：EP1497664A2

  公开（公告）日：2005-01-19
• Method of detecting and locating traces of blood and a compound for detecting traces of blood
  申请人：Lefebvre-Despeaux Jean-Marc

  公开号：US20050176082A1

  公开（公告）日：2005-08-11

  The invention relates to a composition for the detection of traces of human or animal blood. The aforementioned composition comprises a luminol compound, an oxidising agent and a base which are diluted in a preferably aqueous solvent. Said composition is characterized in that: the luminol compound is present in a quantity providing a concentration of between 1 and 20 mmoles/l in the end composition, the oxidizing agent is hydrogen peroxide which is present at a concentration of between 25 and 100 mmoles/l in the end composition, the base is soda, NaOH, which is present at a concentration of between 25 mmoles/l and 500 mmoles/l in the end composition. The invention also relates a kit and a method for preparing said composition. Furthermore, the invention relates to a method of detecting and locating traces of human or animal blood.
• US7662639B2
  申请人：——

  公开号：US7662639B2

  公开（公告）日：2010-02-16