chloro(chloromethyl)ethoxymethylsilane | 1627-97-0

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: chloro(chloromethyl)ethoxymethylsilane
• 英文别名: Chlormethyl-methyl-ethoxy-chlorsilan；methylchloromethylethoxychlorosilane；ClCH2(CH3)Si(OEt)Cl；chloro-(chloromethyl)-ethoxy-methylsilane
• CAS: 1627-97-0
• 化学式: C₄H₁₀Cl₂OSi
• 分子量: 173.114
• InChiKey: QJWUHZAGWZSBDO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.11
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  chloro(chloromethyl)ethoxymethylsilane 在 magnesium 、 碘甲烷 作用下， 以 四氢呋喃 为溶剂， 生成 1,3-diethoxy-1,3-dimethyl-1,3-disilacyclobutane
  参考文献：
  名称：

  The Preparation of Cyclic Siliconmethylene Compounds

  摘要：

  DOI：

  10.1021/jo01029a081
• 作为产物：
  描述：

  (氯甲基)甲基二乙氧基硅烷 、 (氯甲基)甲基二氯硅烷 生成 chloro(chloromethyl)ethoxymethylsilane
  参考文献：
  名称：

  摘要：

  The kinetics or etherification of organochlorosilanes with various substituents on the silicon atom with ethanol were studied. The etherification rate is mostly controlled by the inductive constants of the substituents and increases as the electron-acceptor power of the substituents increases. The rho* value in the Taft equation for etherification of organochlorosilanes with ethanol was determined.

  DOI：

  10.1023/a:1013145419084

文献信息

• Some regularities of chlorosilanes etherification
  作者：Z. V. Belyakova、E. A. Komarov、V. G. Bykovchenko、O. L. Ershov、E. A. Chernyshev、P. A. Storozhenko

  DOI：10.1134/s1070363209080118

  日期：2009.8

  The influence of reagents, solvent polarity, and temperature on the etherification of chlorosilanes ClCH2SiCl3, VinSiCl(3), PrSiCl3, and Ph3SiCl with ethanol was studied. Influence of reaction temperature on the ratio of the synthesized alkoxysilane and related side-product siloxane is revealed. Use of excess alcohol is shown to increase the content of siloxane. Introduction of FeCl3 does not affect the synthesis. Solvents are shown to influence the reaction rate: the rate constant increases with increasing epsilon parameter of the solvent. The rate constant of etherification of chlorosilanes with ethanol falls in the series: ClCH2SiCl3 > VinSiCl(3) > PrSiCl3. An explanation of the regularities is suggested.
• ——
  作者：E. A. Chernyshev、Z. V. Belyakova、E. A. Komarov、V. G. Bykovchenko

  DOI：10.1023/a:1013145419084

  日期：——

  The kinetics or etherification of organochlorosilanes with various substituents on the silicon atom with ethanol were studied. The etherification rate is mostly controlled by the inductive constants of the substituents and increases as the electron-acceptor power of the substituents increases. The rho* value in the Taft equation for etherification of organochlorosilanes with ethanol was determined.
• The Preparation of Cyclic Siliconmethylene Compounds
  作者：William A. Kriner

  DOI：10.1021/jo01029a081

  日期：1964.6