3-Ethyl-2-(2-pyridin-3-ylethenyl)quinazolin-4-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 3-Ethyl-2-(2-pyridin-3-ylethenyl)quinazolin-4-one
• 化学式: C₁₇H₁₅N₃O
• mdl: MFCD01881464
• 分子量: 277.32
• InChiKey: YJAUZTRXBADWHL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  45.6
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Small Molecular Inhibitors of RAD51 Recombinase and Methods Thereof
  申请人：Mazin Alexander V.

  公开号：US20140080849A1

  公开（公告）日：2014-03-20

  The invention includes compositions comprising a selective small-molecule inhibitor of RAD51 recombinase and a pharmaceutically acceptable carrier. The invention further includes methods of treating or preventing cancer in a subject, comprising the step of administering to the subject the compositions contemplated within the invention.
• SMALL MOLECULAR INHIBITORS OF RAD51 RECOMBINASE AND METHODS THEREOF
  申请人：Mazin Alexander V.

  公开号：US20160106751A1

  公开（公告）日：2016-04-21

  The invention includes compositions comprising a selective small-molecule inhibitor of RAD51 recombinase and a pharmaceutically acceptable carrier. The invention further includes methods of treating or preventing cancer in a subject, comprising the step of administering to the subject the compositions contemplated within the invention.
• US9216177B2
  申请人：——

  公开号：US9216177B2

  公开（公告）日：2015-12-22
• US9750742B2
  申请人：——

  公开号：US9750742B2

  公开（公告）日：2017-09-05
• [EN] SMALL MOLECULE INHIBITORS OF RAD51 RECOMBINASE AND METHODS THEREOF<br/>[FR] INHIBITEURS À PETITES MOLÉCULES DE LA RECOMBINASE RAD51 ET PROCÉDÉS ASSOCIÉS
  申请人：PHILADELPHIA HEALTH & EDUCATIO

  公开号：WO2013105985A1

  公开（公告）日：2013-07-18

  The invention includes compositions comprising a selective small- molecule inhibitor of RAD51 recombinase and a pharmaceutically acceptable carrier, The invention further includes methods of treating or preventing cancer in a subject, comprising the step of administering to the subject the compositions contemplated within the invention.