(2S,3R)-2-aminotetradeca-4,6-diene-1,3-diol

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (2S,3R)-2-aminotetradeca-4,6-diene-1,3-diol
• 化学式: C₁₄H₂₇NO₂
• 分子量: 241.37
• InChiKey: UWJZVNRNKDOZCA-UONOGXRCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  17
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  66.5
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• USE OF UNSATURATED SPHINGOSINE COMPOUNDS AS CHEMOTHERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER
  申请人：Saba Julie D.

  公开号：US20110098317A1

  公开（公告）日：2011-04-28

  The present invention is directed to unsaturated sphingosine compounds which are useful as therapeutic agents for the treatment of cancer and for the treatment of other diseases including diabetes and infection with intracellular bacteria. This invention is also directed to methods of using the compounds and pharmaceutical compositions comprising the compounds in treating these diseases.
• US8741967B2
  申请人：——

  公开号：US8741967B2

  公开（公告）日：2014-06-03
• US9133097B2
  申请人：——

  公开号：US9133097B2

  公开（公告）日：2015-09-15
• [EN] USE OF UNSATURATED SPHINGOSINE COMPOUNDS AS CHEMOTHERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER<br/>[FR] UTILISATION DE COMPOSÉS DE SPHINGOSINE INSATURÉE EN TANT QU'AGENTS CHIMIOTHÉRAPEUTIQUES POUR LE TRAITEMENT DU CANCER
  申请人：CHILDRENS HOSP & RES CT OAK

  公开号：WO2009076598A1

  公开（公告）日：2009-06-18

  The present invention is directed to unsaturated sphingosine compounds which are useful as therapeutic agents for the treatment of cancer and for the treatment of other diseases including diabetes and infection with intracellular bacteria. This invention is also directed to methods of using the compounds and pharmaceutical compositions comprising the compounds in treating these diseases.