3-ethyl-2,6-dimethylphenol | 66142-76-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 3-ethyl-2,6-dimethylphenol
• CAS: 66142-76-5
• 化学式: C₁₀H₁₄O
• 分子量: 150.221
• InChiKey: DRNBTKBRWOSYSD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3-hydroxy-4-methyl-2H-pyran-2-one 、 2-硝基-2-戊烯 在 aluminum (III) chloride 、 2,6-二叔丁基-4-甲基苯酚 作用下， 以 邻二氯苯 为溶剂， 反应 16.0h， 以81%的产率得到3-ethyl-2,6-dimethylphenol
  参考文献：
  名称：

  完全区域化学控制的高度取代苯酚和苯的合成。

  摘要：

  取代的酚是人体健康，农业和多种合成材料所必需的分子。我们报告了苯酚的化学合成，包括五取代的苯酚，可在任何位置进行可编程取代。该方法使用易得的羟基吡喃酮和硝基烯烃原料的一步转化，以完全的区域化学控制和高化学收率得到苯酚。另外，苯酚可以转化为高度甚至完全取代的苯。

  DOI：

  10.1021/acs.orglett.0c02157

文献信息

• REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS
  申请人：Oregon State University

  公开号：US20230117370A1

  公开（公告）日：2023-04-20

  Disclosed herein are embodiments of a method for making substituted compounds with specific and selectable regiochemistry. Also disclosed are compounds made by the method. The method may comprise contacting a compound having a formula I with a compound according to formula II in the presence of a Lewis acid to form a phenol compound according to formula III and/or a benzofuranone compound according to formula IV

  本文公开了一种制造具有特定和可选择区域化学性质的取代化合物的方法的实施例。还公开了用该方法制得的化合物。该方法可包括将具有式 I 的化合物 与根据式 II 的化合物接触 在路易斯酸存在下，生成根据式 III 的苯酚化合物和/或根据式 IV 的苯并呋喃酮化合物
• Polyphenylene ether resin composition of improved heat stability and shaped articles thereof
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：EP0036278A1

  公开（公告）日：1981-09-23

  A polyphenylene ether resin composition having improved heat stability, comprises a matrix of polyphenylene ether resin and dispersed therein, as stabilizer, a phosphonous acid or esterthereof of the formula wherein R1 represents an alkyl group, an aryl group which may be substituted by an alkyl group, an aralkyl group which may be substituted by an alkyl group, or a group of the formula (a) in which R. groups are identical or different alkyl groups, and R, and R, are identical or different and each represents a hydrogen atom, an alkyl group, an aryl group which may be substituted by an alkyl group, or an aralkyl group which may be substituted by an alkyl group, provided that when R, represents the group of formula (a), R, and R3 represent identical or different 2,4-dialkylphenyl groups.

  一种具有更好热稳定性的聚苯醚树脂组合物，包括聚苯醚树脂基体和分散在其中的 作为稳定剂的磷酸或其酯，其式如下 其中 R1 代表烷基、可被烷基取代的芳基、可被烷基取代的芳烷基或式（a）的基团 其中 R.基团是相同或不同的烷基，且 R，和 R，是相同或不同的，且各自代表氢原子、烷基、可被烷基取代的芳基或可被烷基取代的芳烷基，但当 R 代表式（a）的基团时，R，和 R3 代表相同或不同的 2，4-二烷基苯基。
• Polyphenylene ether resin compositions and shaped articles thereof
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：EP0038183A1

  公开（公告）日：1981-10-21

  A polyphenylene ether resin composition comprises a polyphenylene ether resin matrix and dispersed therein as heat stabilizer a phosphonic acid or derivative thereof of the formula wherein R1 represents an unsubstituted or substituted phenyl or naphthyl group, or a linear or branched alkyl group of 1 to 18 carbon atoms, or a group of the formula (a) R2 and R3 are the same or different and each represents hydrogen atom, a metal, an unsubstituted or substituted phenyl group, or an alkyl group of 1 to 10 carbon atoms and R4 is a divalent hydrocarbon group of 2 to 10 carbon atoms.

  一种聚苯醚树脂组合物，包括聚苯醚树脂基体和分散在其中的作为热稳定剂的 式中的膦酸或其衍生物 其中 R1 代表未取代或取代的苯基或萘基，或 1 至 18 个碳原子的直链或支链烷基， 或式(a)的基团 R2 和 R3 相同或不同，各自代表氢原子、金属、未取代或取代的苯基或 1 至 10 个碳原子的烷基，R4 是 2 至 10 个碳原子的二价烃基。
• Polyphenylene ether resin composition
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：EP0099230A1

  公开（公告）日：1984-01-25

  A polyphenylene ether resin composition comprising (1) a polyphenylene ether resin, (2) an oxanilide represented by the following formula wherein R' and R6 are identical or different and each represents a hydrogen atom. an alkyl group having 1 to 8 carbon atoms or an alkoxy group having 1 to 15 carbon atoms. R2 and R are identical or different and each represents a hydrogen atom, an alkyl group having 1 to 8 carbon atoms or an alkoxy group having 1 to 10 carbon atoms. R3 and R6 are identical or different and each represents a hydrogen atom or an alkyl group having 1 to 8 carbon atoms and R4 and R5 are identical or different and each represents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, or a dialkylaminoalkyl group with the alkyl moiety having 1 to 6 carbon atoms, and (3) an organic phosphite.

  一种聚苯醚树脂组合物，包括 (1) 聚苯醚树脂、 (2) 下式所代表的草酰苯胺 其中 R' 和 R6 相同或不同，各自代表氢原子、具有 1 至 8 个碳原子的烷基或具有 1 至 15 个碳原子的烷氧基。R2 和 R 相同或不同，各自代表氢原子、具有 1 至 8 个碳原子的烷基或具有 1 至 10 个碳原子的烷氧基。R3 和 R6 相同或不同，各自代表一个氢原子或一个具有 1 至 8 个碳原子的烷基；R4 和 R5 相同或不同，各自代表一个氢原子、一个具有 1 至 6 个碳原子的烷基或一个具有 1 至 6 个碳原子的烷基的二烷基氨基烷基；以及 (3) 有机亚磷酸酯。 (3) 有机亚磷酸酯。
• Process for producing polyphenylene oxides
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：EP0153074A2

  公开（公告）日：1985-08-28

  A process for producing a polyphenylene oxide which comprises oxidatively polycondensing at least one phenol in the presence of a catalyst composed of a cuprous salt and a primary or secondary amine in a mixed solvent consisting of 1 part by weight of a good solvent for the resulting polyphenylene oxide and 0.9 to 1.1 parts by weight of a poor solvent for the resulting polyphenylene oxide. The polyphenylene oxide has superior heat resistance such that it has a glass transition point at least 5°C higher than that of a polyphenylene oxide having the same structural units and produced by a known solution polymerization method.

  一种生产聚苯醚的工艺，包括在一种由亚铜盐和伯胺或仲胺组成的催化剂存在下，在一种混合溶剂中氧化缩聚至少一种苯酚，该混合溶剂由按重量计的1份所得聚苯醚的良好溶剂和按重量计的0.9至1.1份所得聚苯醚的不良溶剂组成。 该聚苯醚具有优异的耐热性，其玻璃化转变点比具有相同结构单元并用已知溶液聚合法生产的聚苯醚的玻璃化转变点至少高5℃。