[3-(2-Hydroxyethyl)-2-methylnonadecan-2-yl]azanium;chloride

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: [3-(2-Hydroxyethyl)-2-methylnonadecan-2-yl]azanium;chloride
• 化学式: C22H48ClNO
• 分子量: 378.1
• InChiKey: BBFUDWWYDBWIJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.88
• 重原子数：
  25
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  47.9
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• ANTIMICROBIAL POLYMERS AND THEIR USES
  申请人：DSM IP Assets B.V.

  公开号：EP2309851A2

  公开（公告）日：2011-04-20
• ANTIMICROBIAL THERMOPLASTIC POLYURETHANES
  申请人：Lubrizol Advanced Materials, Inc.

  公开号：EP3574032B1

  公开（公告）日：2022-08-31
• Antimicrobial, Non-Thrombogenic Polymer Composition
  申请人：Lubrizol Advanced Materials, Inc.

  公开号：US20210277231A1

  公开（公告）日：2021-09-09

  The disclosed technology provides thermoplastic polyurethane compositions having antimicrobial properties while still maintaining good physical properties and good non-fouling properties, methods of making the same, and articles, including medical devices, made from such compositions. The disclosed technology includes a process of making an antimicrobial polymer composition, where the process includes mixing an antimicrobial additive into a base polymer and further includes mixing in a non-fouling additive, where the antimicrobial additive is chemically held in the composition and the antimicrobial and non-fouling additives do not negatively impact each other's effectiveness.
• [EN] ANTIMICROBIAL POLYMERS AND THEIR USES<br/>[FR] POLYMÈRES ANTIMICROBIENS ET LEURS UTILISATIONS
  申请人：DSM IP ASSETS BV

  公开号：WO2009148880A2

  公开（公告）日：2009-12-10

  Polymers with non-leaching antimicrobial activity and their use as surface coatings or bulk resins for medical devices. The antimicrobial polymers are prepared with antimicrobial moieties covalently bonded to a polymer chain end or to a polymer backbone at a side chain end. The antimicrobial moiety-containing endgroups include surface active (or surface assembling) moieties which promote enrichment of antimicrobial endgroups at the polymer surface and thus formation of an antimicrobially active surface. Polymers with built-in antimicrobial endgroups can be used as bulk resins, as antimicrobial additives, or as infection preventative coatings in the manufacture of medical devices (e.g., catheters, vascular access devices, peripheral lines, IV sites, drains, gastric feeding and tubes, and other implantable devices). Such materials can also be used as antimicrobial and antifouling coatings on structures in contact with microorganism in environments that require control of biofilm formation, such as marine products.
• [EN] ANTIMICROBIAL THERMOPLASTIC POLYURETHANES<br/>[FR] POLYURÉTHANNES THERMOPLASTIQUES ANTIMICROBIENS
  申请人：LUBRIZOL ADVANCED MAT INC

  公开号：WO2018140910A1

  公开（公告）日：2018-08-02

  The disclosed technology provides thermoplastic polyurethane compositions having non-leaching antimicrobial properties while still maintaining good physical properties, methods of making the same, and articles, including medical devices, made from such compositions. The disclosed technology includes a process of making an antimicrobial polymer composition, where the process includes mixing an antimicrobial additive into a polymeric material; wherein said polymeric material comprises a polymeric backbone made up of urethane linkages derived from a polyisocyanate and a polyol; and wherein said mixing occurs under conditions that result in the breaking of a minority of said urethane bonds resulting in reactive isocyanate groups; and wherein two or more of said reactive isocyanate groups react with said antimicrobial additive to covalently bond said antimicrobial additive into the polymeric backbone of said polymeric material; resulting in an antimicrobial polymer composition.