8-Ethyl-7-fluoro-2-methoxyquinoxaline

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 8-Ethyl-7-fluoro-2-methoxyquinoxaline
• 英文别名: 8-ethyl-7-fluoro-2-methoxyquinoxaline
• 化学式: C₁₁H₁₁FN₂O
• 分子量: 206.22
• InChiKey: MFISTRAKEQWCAG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  35
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES<br/>[FR] DÉRIVÉS DE 2-HYDROXYCYCLOALCANE-1-CARBAMOYLE
  申请人：IDORSIA PHARMACEUTICALS LTD

  公开号：WO2021028570A1

  公开（公告）日：2021-02-18

  The present invention relates to compounds of Formula (I) wherein Ar1, Ar2, L, n, and R1 are as described in the description, their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of Formula (I), and especially to their use as Galectin-3 inhibitors.