Pentylsulfanylurea

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫基化合物
• 英文名称: Pentylsulfanylurea
• 化学式: C₆H₁₄N₂OS
• 分子量: 162.26
• InChiKey: RCNKDNMYCDQMKB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  80.4
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• PURINONE DERIVATIVES AS HM74A AGONISTS
  申请人：Zheng Changsheng

  公开号：US20080045554A1

  公开（公告）日：2008-02-21

  The present invention relates to purinone derivatives which are agonists of the HM74a receptor. Further provided are compositions and methods of using the compounds herein, and their pharmaceutically acceptable salts for the treatment of disease.

  本发明涉及嘌呤酮衍生物，其为HM74a受体激动剂。此外，还提供了本文化合物的组合物和使用方法，以及它们的药用盐，用于治疗疾病。
• PYRROLIDINES AND PIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS
  申请人：Aissaoui Hamed

  公开号：US20100197733A1

  公开（公告）日：2010-08-05

  The invention relates to compounds of formula (I) wherein Y, A, N and R 1 are as described in the description, to salts, especially pharmaceutically acceptable salts, of such compounds and to the use of such compounds as medicaments, especially as orexin receptor antagonists.

  该发明涉及式（I）中的化合物，其中Y、A、N和R1如描述中所述，以及这些化合物的盐，特别是药用盐，以及将这些化合物用作药物，特别是作为促进睡眠的药物。
• N-Acylthiourea and N-Acylurea Inhibitors of the Hedgehog Protein Signalling Pathway
  申请人：Ruat Martial

  公开号：US20110275663A1

  公开（公告）日：2011-11-10

  The present invention relates to the use of acylthiourea or acylurea derivatives for the treatment of pathologies involving a tissue dysfunction associated with a deregulation of the Hedgehog protein signalling pathway, and also to novel acylthiourea or acylurea derivatives as such, to their use as a medicinal product, and to pharmaceutical compositions containing them.

  本发明涉及使用酰基硫脲或酰基脲衍生物治疗涉及组织功能障碍的病理情况，该功能障碍与Hedgehog蛋白信号通路的失调有关，并且涉及作为药物产品的新型酰基硫脲或酰基脲衍生物，它们的用途以及含有它们的药物组成物。
• Purinone Derivatives as HM74A Agonists
  申请人：Zheng Changsheng

  公开号：US20120035172A1

  公开（公告）日：2012-02-09

  The present invention relates to purinone derivatives which are agonists of the HM74a receptor. Further provided are compositions and methods of using the compounds herein, and their pharmaceutically acceptable salts for the treatment of disease.

  本发明涉及嘌呤酮衍生物，其是HM74a受体的激动剂。还提供了本文化合物的组合物和使用方法，以及它们的药学上可接受的盐，用于治疗疾病。
• Method and material for the formation of silver halide color photographic image
  申请人：KONICA CORPORATION

  公开号：EP0073146A1

  公开（公告）日：1983-03-02

  A novel class of phenol cyan couplers are described. These couplers have in the two position a phenyl ureido group substituted by an alkyl, aryl, heterocyclic, hydroxy, alkoxy, aryloxy, acyloxy, alkyl-thio, acylamino or sulfonamide group; which has in the four position thereof a hydrogen atom or an atom or group capable of being eliminated during coupling with the oxidation product of a color developing agent; and which has in the five position thereof an acylamino group.

  本文描述了一类新型的苯酚氰基偶联剂，这些偶联剂在 2 位上有一个被烷基、芳基、杂环基、羟基、烷氧基、芳氧基、酰氧基、烷硫基、酰氨基或磺酰胺基取代的苯基脲基；在 4 位上有一个氢原子或在与显色剂的氧化产物偶联时能够被消除的原子或基团；在 5 位上有一个酰氨基。